Baboon models of E.coli sepsis: role of phospholipid microparticles in disseminated intravascular Coagulation
- Authors: Taylor Jr. F.B.1
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Affiliations:
- Medical Research Foundation
- Issue: Vol 80, No 5 (1999)
- Pages: 340-352
- Section: Articles
- URL: https://journals.rcsi.science/kazanmedj/article/view/70171
- DOI: https://doi.org/10.17816/kazmj70171
- ID: 70171
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Abstract
The experiences with primate models of E.coli sepsis with emphasis on the responses of the hemostatic system and the mechanism of these responses with emphasis on the role of phospholipid microparticles in mediating disseminated intravascular coagulation, (DIC) are discribed. Understanding the principles of how the hemostatic system responds to inflammatory stress depends on viewing this system as a collection of mediator and regulator factors. They are integrated into a balanced system consisting of four functional quadrants. Depending on circumstances this system is designed to control either the patency or the integrity of the cardiovascular system.
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##article.viewOnOriginalSite##About the authors
F. B. Taylor Jr.
Medical Research Foundation
Author for correspondence.
Email: info@eco-vector.com
United States, Oklahoma
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