Influence of influenza infection on the intensity of antitoxic immunity and the incidence of diphtheria in vaccinated children

Abstract

According to a number of authors, the strength of immunity against diphtheria drops sharply after suffering infectious diseases, in particular influenza. To clarify this question, in March — April 1962, we 1252 children aged 7 to 12 years 6 months after the initially delivered Schick reaction (all of them negative), 1½ — 2 months after the flu, we repeated the Schick reaction. It turned out that only in 7 children it was possible to associate a drop in immunity to diphtheria (up to a weakly positive Schick reaction) with an influenza infection.

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