Experimental assessment of potassium ions diffusion speed from new gel reducing dental sensitivity
- Authors: Kozmenko AN1, Belokonov NA1
-
Affiliations:
- Ural State Medical University, Yekaterinburg, Russia
- Issue: Vol 95, No 5 (2014)
- Pages: 675-679
- Section: Theoretical and clinical medicine
- URL: https://journals.rcsi.science/kazanmedj/article/view/2214
- DOI: https://doi.org/10.17816/KMJ2214
- ID: 2214
Cite item
Full Text
Abstract
Aim. To compare the contents of potassium salts in specialized toothpastes, and to estimate the possibility for potassium ions diffusion through dentinal tubules after firm tooth tissues conditioning by a toothpaste containing fluoride. Methods. Toothpastes specially formulated to treat the pain of sensitive teeth: «Sensodyne F» (contains potassium chloride); «PresiDENT Sensitive» (potassium nitrate); «Asepta Sensitive» (potassium citrate) and new gel reducing dental sensitivity (contains potassium chloride) were examined. Speed of potassium ions diffusion through dentinal tubules after firm tooth tissues conditioning by a toothpaste containing fluoric substances were measures by potentiometry and a special device using tooth slice as a membrane. Results. Considering that toothpaste is applied within 5 minutes, while gel - within 15-20 minutes, it is possible to assume that potassium ions bioavailability from 1 g of gel can be assessed as 41 mg, compared to 5.9±0.5 mg from 1 g of paste №1, 0.4±0.05 mg - №2; 7.8±0.5 mg - №3. So, potassium ions bioavailability from 1 g of gel is 7; 102; 5 times higher (respectively) compared to toothpastes. Speed of potassium ions diffusion through dentinal tubules ranged between 0.2 to 1.64 μg/min and depended on the number of membrane potassium channels permeable for potassium. Fluoride toothpastes specially formulated to treat the pain of sensitive teeth reduced the speed of potassium ions diffusion from the solution by 4-7 times by blocking the dentinal tubules. This can be also associated with fluoride-containing protective film formation. Therefore, at the first stage of treatment of teeth hypersensitivity using new gel, it is better to use a toothpaste without fluoride. Conclusion. Compared to the examined toothpastes, new gel for reducing dental sensitivity contains higher number of potassium free ions, which can enter dentinal tubules reducing the effect on free nerve endings. Potassium ions diffusion through dentinal tubules reduced 4-7-fold after conditioning by a toothpaste containing fluoride.
Full Text
##article.viewOnOriginalSite##About the authors
A N Kozmenko
Ural State Medical University, Yekaterinburg, Russia
Email: power2030@yandex.ru
N A Belokonov
Ural State Medical University, Yekaterinburg, Russia
References
- Белоконова Н.А., Ронь Г.И., Козьменко А.Н., Перевалов С.Г. Устройство для оценки скорости диффузии электролита через дентинные канальцы. Патент на полезную модель №138749. Бюлл. №8 от 20.03.2014.
- Будзинский Н.Э., Сирак А.Г., Арутюнов А.В. Сравнительный анализ эффективности лечения гиперестезии твёрдых тканей зубов с использованием препаратов на основе соединений фтора и глутаральдегида // Соврем. пробл. науки и образования. - 2014. - №1. - С. 133-140.
- Вольф Г.Ф., Хэссел Т.М. Пародонтология. Гигиенические аспекты / Под ред. Г.И. Ронь. - М.: Медпресс-информ, 2014. - 360 с.
- Руле Ж.Ф., Циммер C. Профессиональная профилактика в практике стоматолога: атлас по стоматологии / Под общ. ред. С.Б. Улитовского, С.Т. Пыркова. - М.: МЕДпресс-информ, 2010. - 368 с.
- Улитовский С.Б. Гигиена полости рта в пародонтологии. - М.: Медицинская книга, 2006. - 268 с.
- Хамадеева А.М., Комарина Т.А. Планирование лечения гиперстезии зубов // Институт стоматол. - 2006. - Т.3; №32. - С. 72-77.
- Addy M., Smith S.R. Dentin hypersensitivity: an overview on which to base tubule occlusion as a management concept // J. Clin. Dent. - 2010. - Vol. 21. - P. 25-30.
- Cummins D.J. Dentin hypersensitivity: from diagnosis to a breakthrough therapy for everyday sensitivity relief // Clin. Dent. - 2009. - Vol. 20, N 1. - P. 1-9.
- Day T., Einwag J., Hermann J. et al. A clinical assessment of the efficacy of a stannous-containing sodium fluoride dentifrice on dentinal hypersensitivity // J. Contemp. Dent. Pract. - 2010. - Vol. 11, N 1. - P. 1-8.