Experimental pharmacotherapy of toxic brain edema by nonanticholinesterasic phosphoroorganic compounds
- Authors: Khafizyanova R.H.1
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Affiliations:
- Kazan Medical University
- Issue: Vol 76, No 3 (1995)
- Pages: 198-201
- Section: Pharmacy
- URL: https://journals.rcsi.science/kazanmedj/article/view/100634
- DOI: https://doi.org/10.17816/kazmj100634
- ID: 100634
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Abstract
Experimental study of the effect of dimephosphone, phosphabenzide, preparations № 305 and № 155 — examples of various groups of synthetic nonanticholinesterasic phosphoroorganic compounds, on the development of toxic brain edema in rats, caused by injection of nicotine and monoiodacetate, reveal their antiedematic property. The results of investigations show prospects of a search of new effective medicinal agents for prevention and treatment of brain edema among phosphoroorganic compounds which do not show anticholinesttrasic activity.
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##article.viewOnOriginalSite##About the authors
R. H. Khafizyanova
Kazan Medical University
Author for correspondence.
Email: info@eco-vector.com
Department of Pharmacology
Russian Federation, KazanReferences
