Endogenous inhibitors of the Na, K-ATPase in preeclampsia

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Objectives: Previously we have shown, that mammalian tissues contain a steroidal inhibitor of Na, K-ATPase which is similar to Amphibian vasoconstrictor hormone, marinobufagenin (MBG). The mammalian MBG is implicated in plasma volume dependent forms of hypertension. We compared plasma levels of MBG, in normotensive pregnancy and in preeclampsia with that of ouabain-like compound (OLC), and characterized the partially purified MBG immunoreactive factor from preeclamptic plasma.

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D. Lopatin

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

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俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

E. Ailamazian

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

R. Dmitrieva

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

O. Fedorova

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

N. Kolodkin

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

A. Bagrov

D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging

Email: info@eco-vector.com
俄罗斯联邦, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA

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