Email this article Endogenous inhibitors of the Na, K-ATPase in preeclampsia
- Authors: Lopatin D.A.1,2,3,4, Ailamazian E.K.1,2,3,4, Dmitrieva R.I.1,2,3,4, Fedorova O.V.1,2,3,4, Kolodkin N.I.1,2,3,4, Bagrov A.Y.1,2,3,4
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Affiliations:
- D.O. Ott Institute of Obstetrics and Gynecology
- Sechenov Institute of Evolutionary Physiology and Biochemistry
- Verta peptids inc.
- National Institute on Aging
- Issue: Vol 48, No 5S (1999)
- Pages: 103-103
- Section: Articles
- URL: https://journals.rcsi.science/jowd/article/view/101155
- DOI: https://doi.org/10.17816/JOWD101155
- ID: 101155
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Abstract
Objectives: Previously we have shown, that mammalian tissues contain a steroidal inhibitor of Na, K-ATPase which is similar to Amphibian vasoconstrictor hormone, marinobufagenin (MBG). The mammalian MBG is implicated in plasma volume dependent forms of hypertension. We compared plasma levels of MBG, in normotensive pregnancy and in preeclampsia with that of ouabain-like compound (OLC), and characterized the partially purified MBG immunoreactive factor from preeclamptic plasma.
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##article.viewOnOriginalSite##About the authors
D. A. Lopatin
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
E. K. Ailamazian
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
R. I. Dmitrieva
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
O. V. Fedorova
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
N. I. Kolodkin
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
A. Y. Bagrov
D.O. Ott Institute of Obstetrics and Gynecology; Sechenov Institute of Evolutionary Physiology and Biochemistry; Verta peptids inc.; National Institute on Aging
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg; St. Petersburg; Baltimore, USA
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