Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia

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Abstract

To determine the role of cytokines in pathogenesis of pre-eclampsia, production of IL1/3, IL4, IL6 and TNFa by chorionic villous explant of healthy women and patients with pre-eclampsia under the influence of hypoxia was investigated. The results received testify to considerable changes of cytokine production connected with the form of pre-eclampsia. So, placenta as a source of cytokines in case of pre-eclampsia appears to injure endothelium.

About the authors

A. Ju. Krivoruchko

Stavropol State Medical Academy

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Stavropol

V. A. Aksenenko

Stavropol State Medical Academy

Email: info@eco-vector.com
Russian Federation, Stavropol

A. N. Kvochko

Stavropol State Medical Academy

Email: info@eco-vector.com
Russian Federation, Stavropol

R. V. Pavlov

Stavropol State Medical Academy

Email: info@eco-vector.com
Russian Federation, Stavropol

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