Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia

A. Ju. Krivoruchko; Криворучко А. Ю.; V. A. Aksenenko; Аксененко В. А.; A. N. Kvochko; Квочко А. Н.; R. V. Pavlov; Павлов Р. В.

doi:10.17816/JOWD89483

Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia

Authors: Krivoruchko A.J.¹, Aksenenko V.A.¹, Kvochko A.N.¹, Pavlov R.V.¹
Affiliations:
1. Stavropol State Medical Academy
Issue: Vol 49, No 4 (2000)
Pages: 82-85
Section: Discussions
URL: https://journals.rcsi.science/jowd/article/view/89483
DOI: https://doi.org/10.17816/JOWD89483
ID: 89483

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Abstract

To determine the role of cytokines in pathogenesis of pre-eclampsia, production of IL1/3, IL4, IL6 and TNFa by chorionic villous explant of healthy women and patients with pre-eclampsia under the influence of hypoxia was investigated. The results received testify to considerable changes of cytokine production connected with the form of pre-eclampsia. So, placenta as a source of cytokines in case of pre-eclampsia appears to injure endothelium.