Cytokine production by chorionic villous explant in case of preeclampsia under hypoxia
- Authors: Krivoruchko A.J.1, Aksenenko V.A.1, Kvochko A.N.1, Pavlov R.V.1
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Affiliations:
- Stavropol State Medical Academy
- Issue: Vol 49, No 4 (2000)
- Pages: 82-85
- Section: Discussion
- URL: https://journals.rcsi.science/jowd/article/view/89483
- DOI: https://doi.org/10.17816/JOWD89483
- ID: 89483
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Abstract
To determine the role of cytokines in pathogenesis of pre-eclampsia, production of IL1/3, IL4, IL6 and TNFa by chorionic villous explant of healthy women and patients with pre-eclampsia under the influence of hypoxia was investigated. The results received testify to considerable changes of cytokine production connected with the form of pre-eclampsia. So, placenta as a source of cytokines in case of pre-eclampsia appears to injure endothelium.
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##article.viewOnOriginalSite##About the authors
A. Ju. Krivoruchko
Stavropol State Medical Academy
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Stavropol
V. A. Aksenenko
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation, Stavropol
A. N. Kvochko
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation, Stavropol
R. V. Pavlov
Stavropol State Medical Academy
Email: info@eco-vector.com
Russian Federation, Stavropol