Possibilities of HRT in solving the problem of psychosocial adaptation of girls with primary estrogen deficiency

This study presents the results of testing the hypothesis that girls during the period of normally proceeding puberty experience much more emotional discomfort, difficulties in communication and self-acceptance due to more pronounced hormonal and bodily changes than normally developing boys. Along with this, for the first time, results are presented that indicate some similarity of adaptive responses in boys with normal puberty and in girls with primary estrogen deficiency on the background of hormone replacement therapy (HRT). The development of girls with 45×0-gonadal dysgenesis (with Turner syndrome) on the background of HRT is considered as adaptive to the tasks of age, less than their passport data. Girls with XY-sex reversion with gonadal dysgenesis are assessed as sufficiently adapted due to certain personal and age characteristics.