The alteration of serum protein sensibility to oxidation at pregnancy

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Abstract

The article presents data on the protein peroxidation products (PPP) serum contents alteration at pregnancy. PPP are produced under the influence of reactive oxygen species (ROS). The level of PPP during spontaneous oxidation slightly decreased in serum from pregnant women. However, the PPP content was significantly elevated under the influence of Fe2+-ions and H2O2 at pregnancy. The data obtained testify to serum proteins being more sensitive to oxidation by ROS at pregnancy.

About the authors

O. S. Burmistrov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Saint Petersburg

T. I. Oparina

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

А. V. Arutjunyan

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: info@eco-vector.com
Russian Federation, Saint Petersburg

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Supplementary files

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1. JATS XML
2. Fig. Absorption spectrum of products of protein peroxidation:

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