Systemic and local levels of regulation of immunopathogenetic processes in patients with external genital endometriosis

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Abstract

The article represents the authors’ data, gained during studies of systemic and local mechanisms of regulation of immune processes in pathogenesis of external genital endometriosis. Research was carried out into spectrum and production of some cytokines, growth factors by endometrioid heterotopias under condition of organotypic cultivation compared to secretary activity of cells in peritoneal fluid and endometrial tissue in women with endometriosis.

About the authors

S. A. Selkov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

M. I. Yarmolinskaya

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

O. V. Pavlov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

D. I. Sokolov

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

V. V. Grigorijeva

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

N. L. Kramareva

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

N. G. Solodovnikova

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

D. A. Niauri

Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Otta

Author for correspondence.
Email: jowd@eco-vector.com
Russian Federation, Saint Petersburg

References

Supplementary files

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2. Fig. 1. The content of IL-8 and IL-6 in the supernatants of endometrioid heterotopies

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3. Fig. 2. Content of IL-2, TNF and IL-Ib in supernatants of endometrioid heterotopies

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4. Fig. 3. Interleukin-Ib content in supernatants of endometrioid heterotopies depending on the degree of IGE prevalence

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5. Fig. 4. IL-6 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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6. Fig. 5. IL-8 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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7. Fig. 6. IL-2 content in supernatants of endometrioid heterotopies depending on the prevalence of IGE

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8. Fig. 7. Content of IL-8 and IL-6 in endometrial supernatants from patients with EGE

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9. Fig. 8. Content of IL-2, TNF and IL-1b in endometrial supernatants from patients with EGE

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10. Fig. 9. Content of IL-8 and IL-6 in endometrial supernatants from EGE patients and the control group

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Copyright (c) 2005 Eсо-Vector



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