III. Immaturity of the lungs: neonatal perspective - could we influence the fetal lung maturity?

Abstract

Could we influence the fetal lung maturity? Many experimental and clinical studies can give us a positive answer. It is well known that fetal lung maturation is affected by a number of hormones and pharmacological agents, including adrenocorticotropic hormone (ACTH), glucocorticoids, thyrotropin-releasing hormone (TRH), and tri-iodothyronine (T₃); agents influencing the intracellular content of cyclic adenosine monophosphate (cAMP), such as beta-adrenergic agonists and aminophylline; substances increasing intracellular calcium or acting on protein kinase C, etc.

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