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Post a Comment Sensitive periods in development of endometriosis
- Authors: Baranov V.1
-
Affiliations:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 16, No 2 (2018)
- Pages: 36-39
- Section: Human ecological genetics
- URL: https://journals.rcsi.science/ecolgenet/article/view/8837
- DOI: https://doi.org/10.17816/ecogen16236-39
- ID: 8837
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Abstract
The hypothesis of three sensitive periods (SP) in development of common gynecological disease – external endometriosis (EM) is suggested: I – prenatal female genital system development from the stem cells (SC) of Mullerian ducts; II – uterine endometrial cells transition into mesenchymal meSC; III – endometriotic lesions implantation and growth within pelvic lining. Genetic and epigenetic drivers operative at each SP of EM are outlined and their implication for understanding EM origin and development are briefly discussed.
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##article.viewOnOriginalSite##About the authors
Vladislav Baranov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: baranov@vb2475.spb.edu
ORCID iD: 0000-0002-6518-1207
SPIN-code: 9196-7297
PhD, Associate professor, Department of genetics and biotechnology
Russian Federation, 3, Mendeleevskaya line, Saint Petersburg, 199034
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