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Post a Comment MODERN TRANSARTERIAL CHEMOEMBOLIZATION AS A STEP TOWARDS THE TREATMENT OF MALIGNANTTUMORS OF THE UTERI AND CERVIX
- Authors: Lebedev DP1, Kedrova AG1, Astakhov DA1, Shablovsky OR1, Wanke NS1
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Affiliations:
- Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА России
- Issue: Vol 7, No 2 (2016)
- Pages: 50-57
- Section: Articles
- URL: https://journals.rcsi.science/clinpractice/article/view/8099
- DOI: https://doi.org/10.17816/clinpract7250-57
- ID: 8099
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Abstract
Introduction: Advanced cases of carcinomas with parametrial and fornix infiltration often cause massive genital bleeding, with severe anemia, fast deterioration, and a high risk of death for patients. One method of stoped bleeding is transarterial chemoembolization, which has been studied. Methods: Seven women with advanced uterine and cervix cancer or the pelvic locoregional recurrence withgenital massive bleeding were treated using an endovascular therapy (transarterial chemoembolization (TACE) using cisplatin or doxorubicin or gemcitabine). Ware used HepaSphere (Bioshere Medical, France) filled with saturated 50 mg doxorubicin or 500 mg gemcitabine or 50 mg cisplatin. Results: On average, the total operative time for the procedure was 52 minutes. In all cases, the achieved control bleeding. By the 7th day were signs of reduction in tumor size, 1/3 of its original size. The maximum effect on the tumor size was achieved within 14-20 days. In 2 cases, chemoembolization performed twice at an interval of 21 to 28 days, due to a good picture of the ultrasound tumor vascularization. All operations are carried out under the I/V anesthesia and we had no adverse reactions or complications. Conclusions: Arterial chemoembolization dominant vessels tumor is a reliable method of stopping the genital bleeding at any time during of the planned treatment. It is to improve the quality of life of patients. Antitumor efficacy of drug has a lasting effect. The method is applicable as a minimally invasive, effective for treatment of cancer patients.
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##article.viewOnOriginalSite##About the authors
D P Lebedev
Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА Россииврач Центра сердечнососудистой и эндоваскулярной хирургии ФНКЦ ФМБА России
A G Kedrova
Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА России
Email: kedrova.anna@gmail.com
зав. онкологическим отделением ФНКЦ ФМБА России, д.м.н., профессор.
D A Astakhov
Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА Россиик.м.н, врач онкологического отделения ФНКЦ ФМБА, доцент кафедры хирургии ФПДО ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России
O R Shablovsky
Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА Россиизам. главного врача по хирургической помощи,д.м.н., профессор
N S Wanke
Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий ФМБА Россиизав. отделением гинекологии ФНКЦ ФМБА России
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