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Post a Comment EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX
- Authors: Kogan EA1, Ts L.T.1, Faizullina NM2, Kazachenko AV2
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Affiliations:
- ГБОУ ВПО Первый МГМУ им. И.М. Сеченова
- ФГБУ Научный центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздрава России
- Issue: Vol 7, No 1 (2016)
- Pages: 34-38
- Section: Articles
- URL: https://journals.rcsi.science/clinpractice/article/view/8085
- DOI: https://doi.org/10.17816/clinpract7134-38
- ID: 8085
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Abstract
The pathology of cervical HPV infection is detected by three types of epithelial-mesenchymal spheroidal structures: reparative, neoplastic and cancerous involved in reparation processes and in tumor growth. Cancer spheroids are different from neoplastic not only larger in size but also a tendency to merge, and high expression of p53. Expression of tumor markers p53, p16 and Ki-67 could be used in the early differential diagnosis of precancer and squamous cell carcinoma of the cervix.
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##article.viewOnOriginalSite##About the authors
E A Kogan
ГБОУ ВПО Первый МГМУ им. И.М. Сеченовад.м.н., профессор, заведующая кафедрой патологической анатомии ГБОУ Первый медицинский университет им. И.М.Сеченова
Li Ts Ts
ГБОУ ВПО Первый МГМУ им. И.М. Сеченова
N M Faizullina
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздрава России
A V Kazachenko
ФГБУ Научный центр акушерства, гинекологии и перинатологии им. академика В.И. Кулакова Минздрава России
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