A case of aggressive angiomyxoma. Differential diagnosis of abandoned nonorgan organ tumors (literature review with their own clinical observations)

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Abstract

Background. Aggressive angiomyxoma is a rare pelvic-perineal tumor that affects mainly women aged 30–50 years. It can simulate a bartholine cyst, abscess, lipoma, simple labial cyst or other soft tissue tumors of the pelvis. The main features of angiomyxoma are asymptomatic course and absence of metastasis with a tendency to deep invasion and relapses after a surgical treatment.

Clinical Case Description. The article describes a clinical case of aggressive angiomyxoma in a 33-year-old patient who was admitted to the emergency hospital with a suspected right sciatic hernia. According to the results of clinical and radiological examination, the formation of a presacral space was detected spreading to the m. levator ani on the right and into the tissue of the right ischiorectal fossa, infiltrating them. The specific features could not be identified at the initial stage of the diagnosis using the formal signs distinctive for the specific type of neoplasms. The diagnosis was made as a result of the morphological analysis of the surgical resection material of the tumor. The relapse was not detected in the following 6 months. Assuming the high risk of angiomixoma progression, the dynamic monitoring was continued.

Conclusion. This study and the literature data have demonstrated the typical difficulties of the differential diagnosis and prognosis of the disease, the need for a comprehensive approach using multiparametric magnetic resonance imaging, both at the initial stages of examination and when monitoring the effectiveness of treatment.

About the authors

Elena A. Egorova

Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Author for correspondence.
Email: tylsit@mail.ru
ORCID iD: 0000-0003-2580-5692
SPIN-code: 3771-3676

M.D. Med., Professor

Russian Federation, Moscow

Ekaterina A. Shaposhnikova

Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Email: Nice.katrin@mail.ru
ORCID iD: 0000-0001-6466-658X
SPIN-code: 5010-6296
Russian Federation, Moscow

Dmitriy A. Lezhnev

Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Email: lezhnevd@mail.ru
ORCID iD: 0000-0002-7163-2553

M.D. Med., Professor

Russian Federation, Moscow

Elena P. Kleymenova

Municipal Clinical Hospital named after S.S. Yudin, Department of Healthcare of Moscow

Email: kleymenova.e.p@gmail.com
Russian Federation, Moscow

Alexandr V. Bazhin

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Healthcare Department

Email: avbazhin@yandex.ru
ORCID iD: 0000-0003-3198-1334
SPIN-code: 6122-5786

Ph.D. Med.

Russian Federation, Moscow

Margarita V. Semenova

Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Email: mvdoc@mail.ru
ORCID iD: 0000-0003-4607-1819
SPIN-code: 1194-7975

M.D. Med., Professor

Russian Federation, Moscow

Victor P. Truten

Moscow State University of Medicine and Dentistry named after A.I. Evdokimov

Email: VPT177@mail.ru
ORCID iD: 0000-0002-8941-4511
SPIN-code: 3595-3903

M.D. Med., Professor

Russian Federation, Moscow

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Supplementary files

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2. Fig. 2. MR-tomograms of the small pelvis, T2-WI in the sagittal plane (A), T2-WI with suppression of the signal from fat in the coronal plane (B), T1-WI in the axial plane (C), image with a map of the calculated diffusion coefficient in axial plane (D)

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Copyright (c) 2020 Egorova E.A., Shaposhnikova E.A., Lezhnev D.A., Kleymenova E.P., Bazhin A.V., Semenova M.V., Truten V.P.

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