Short-term results of two strategies in thoracoscopic ablation for lone atrial fibrillation

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Abstract

Background: Thoracoscopic ablation is an effective treatment of patients with atrial fibrillation. Nowadays, 2 types of ablative devices are available in clinical practice allowing one to perform the thoracoscopic procedure — Medtronic and AtriCure. However, the contemporary clinical literature does not have enough data that would compare these two approaches. Aims: to perform a comparative analysis of the short-term results of two minimally invasive strategies in thoracoscopic ablation for atrial fibrillation. Methods: 232 patients underwent thoracoscopic ablation for atrial fibrillation in two clinical centers for the period from 2016 to August 2021. The patients were divided into 2 groups. The first group was represented by those patients to whom a Medtronic device was applied (n=140), the second group was treated with an AtriCure device (n=92). The patients were comparable in their age, gender, initial severity of the condition. The follow-up consisted of laboratory tests, chest Х-ray, electrocardiography, 24-hour Holter monitor, echocardiography. The structure and prevalence of postoperative and intraoperative complications, specifics of the postoperative period were compared between the two groups. Results: According to the structure and prevalence of intraoperative complications the 2 groups are comparable to each other: 4.3% and 1.1% for the 1st group and 2nd group, respectively (p >0.05). The postoperative complications had developed in 6 (4.3%) and 5 (5.4%) patients in groups 1 and 2, respectively (p >0.05). At the time of discharge from hospital, a sinus rhythm was registered in 93.6% of patients (1st group), and 85.9% (2nd group) (p <0.05). Conclusions: Both strategies have demonstrated comparable short-term results in patients with lone atrial fibrillation. A further research is needed to evaluate the effectiveness of this strategy in a long-term period.

About the authors

Aleksandr S. Zotov

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: zotov.alex.az@gmail.com
ORCID iD: 0000-0003-0494-0211
SPIN-code: 9315-6570

MD, PhD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Oleg Yu. Pidanov

Clinical City Hospital named after I.V. Davydovsky

Email: 9681@mail.ru
ORCID iD: 0000-0003-2017-9258
SPIN-code: 8264-7791

MD, PhD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Ilkin S. Osmanov

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: dr.osmanov@bk.ru
ORCID iD: 0000-0002-8114-529X
SPIN-code: 9214-2606
ResearcherId: GQP-0474-2022

MD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Aleksandr V. Troitskiy

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: dr.troitskiy@gmail.com
ORCID iD: 0000-0003-2143-8696
SPIN-code: 2670-6662

MD, PhD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Aleksandr A. Silayev

Federal State Budget Institution Clinical hospital

Email: Surgeon-Alex@yandex.ru
ORCID iD: 0000-0002-3798-1936

MD, PhD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Emil' R. Sakharov

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: sakharoom@gmail.com
ORCID iD: 0000-0003-1057-2777
SPIN-code: 6744-9462

MD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Vladimir N. Sukhotin

Federal State Budget Institution Clinical hospital

Email: vladimir.suhotin@yandex.ru
ORCID iD: 0000-0001-6897-4483

MD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Oleg O. Shelest

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: toshelest@gmail.com
ORCID iD: 0000-0002-0087-9049

MD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Robert I. Khabazov

Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency

Email: khabazov119@gmail.com
ORCID iD: 0000-0001-6801-6568

MD, PhD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

Denis A. Timashkov

Federal State Budget Institution Clinical hospital

Author for correspondence.
Email: denistima@gmail.com
ORCID iD: 0000-0003-2831-1284

MD

Russian Federation, 28, Orekhovy blvd, Moscow, 115682

References

  1. Van Laar C., Kelder J., van Putte B.P. The totally thoracoscopic maze procedure for the treatment of atrial fibrillation. Int Cardio Vascular Thoracic Sur. 2017;24(1):102–111. doi: 10.1093/icvts/ivw311
  2. Je H.G., Shuman D.J., Ad N. A systematic review of minimally invasive surgical treatment for atrial fibrillation: a comparison of the Cox-Maze procedure, beating-heart epicardial ablation, and the hybrid procedure on safety and efficacy. Eur J Cardiothoracic Sur. 2015;48(4):531–541. doi: 10.1093/ejcts/ezu536
  3. Haissaguerre M., Jaïs P., Shah D.C., et al. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339(10):659–666. doi: 10.1056/NEJM199809033391003
  4. Kalifa J., Tanaka K., Zaitsev A.V., et al. Mechanisms of wave fractionation at boundaries of high-frequency excitation in the posterior left atrium of the isolated sheep heart during atrial fibrillation. Circulation. 2006;113(5):626–633. doi: 10.1161/CIRCULATIONAHA.105.575340
  5. Todd D.M., Skanes A.C., Guiraudonet G., et al. Role of the posterior left atrium and pulmonary veins in human lone atrial fibrillation: electrophysiological and pathological data from patients undergoing atrial fibrillation surgery. Circulation. 2003; 108 (25): 3108–3114. doi: 10.1161/01.CIR.0000104567.72914.BF
  6. Oral H., Özaydin M., Tada H., et al. Mechanistic significance of intermittent pulmonary vein tachycardia in patients with atrial fibrillation. J Cardiovascul Electrophysiol. 2002; 13 (7): 645–650. doi: 10.1046/J.1540-8167.2002.00645.X
  7. Morillo C.A., Klein G.J., Jones DL, et al. Chronic rapid atrial pacing: structural, functional, and electrophysiological characteristics of a new model of sustained atrial fibrillation. Circulation. 1995; 91 (5):1588–1595. doi: 10.1161/01.CIR.91.5.1588
  8. Kumagai K., Yasuda T., Tojoet H., et al. Role of rapid focal activation in the maintenance of atrial fibrillation originating from the pulmonary veins. Pacing Clin Electrophysiol. 2000;23(11):1823–1827. doi: 10.1111/j.1540-8159.2000.tb07029.x
  9. Roberts-Thomson K.C., Stevenson I.H., Kistler P.M., et al. Anatomically determined functional conduction delay in the posterior left atrium: relationship to structural heart disease. J Am College Cardiol. 2008;51(8):856–862. doi: 10.1016/J.JACC.2007.11.037
  10. Harlaar N., Verberkmoes N.J., van der Voort P.H., et al. Clamping versus nonclamping thoracoscopic box ablation in long-standing persistent atrial fibrillation. J Thoracic Cardiovascul Sur. 2020;160(2):399–405. doi: 10.1016/j.jtcvs.2019.07.104
  11. Пиданов О.Ю., Зотов А.С. Торакоскопическая хирургия фибрилляции предсердий. Москва: Ваш формат, 2020. С. 73–110. [Pidanov OY, Zotov AS. Thoracoscopic surgery of atrial fibrillation. Moscow: Vash format; 2020. Р. 73–110. (In Russ).]
  12. Van Laar C., Geuzebroek G.S., Hofman F.N., van Putte B.P. The totally thoracoscopic left atrial maze procedure for the treatment of atrial fibrillation. Multimedia Manual Cardiothor Sur. 2016;2016:mmv043. doi: 10.1093/mmcts/mmv043
  13. Steinberg J.S., O’Connell H., Li S., Ziegler P.D. Thirty-second gold standard definition of atrial fibrillation and its relationship with subsequent arrhythmia patterns: analysis of a large prospective device database. Circulation Arrhythmia Electrophysiol. 2018; 11(7):e006274. doi: 10.1161/CIRCEP.118.006274
  14. Вачев С.А., Богачев-Прокофьев А.В., Зотов А.С., и др. Хирургическое лечение фибрилляции предсердий: технология выполнения торакоскопической радиочастотной фрагментации левого предсердия // Ангиология и сосудистая хирургия. 2019. Т. 25, № 4. С. 146–158. [Vachev SA, Bogachev-Prokofiev AV, Zotov AS, et al. Surgical treatment of atrial fibrillation: technology for performing thoracoscopic radiofrequency fragmentation of the left atrium. Angiol Vascul Sur. 2019;25(4):146–158. (In Russ).] doi: 10.33529/ANGIO2019416
  15. Vos L.M., Kotecha D., Geuzebroek G.S., et al. Totally thoracoscopic ablation for atrial fibrillation: a systematic safety analysis. Europace. 2018;20(11):1790–1797. doi: 10.1093/europace/eux385
  16. Haldar S., Khan H.R., Boyalla V., et al. Thoracoscopic surgical ablation versus catheter ablation as first-line treatment for long-standing persistent atrial fibrillation: the CASA-AF RCT. Southampton (UK): NIHR Journals Library; 2021. doi: 10.3310/eme08180
  17. Phan K, Phan S, Thiagalingam A, et al. Thoracoscopic surgical ablation versus catheter ablation for atrial fibrillation. Eur J Cardio-Thoracic Sur. 2016;49(4):1044–1051. doi: 10.1093/ejcts/ezv180
  18. Kron J., Kasirajan V., Wood M.A., et al. Management of recurrent atrial arrhythmias after minimally invasive surgical pulmonary vein isolation and ganglionic plexi ablation for atrial fibrillation. Heart Rhythm. 2010;7(4):445–451. doi: 10.1016/j.hrthm.2009.12.008
  19. Stulak J.M., Suri R.M., Burkhar H.M., et al. Surgical ablation for atrial fibrillation for two decades: are the results of new techniques equivalent to the Cox maze III procedure? J Thoracic Cardiovasc Sur. 2014;147(5):1478–1487. doi: 10.1016/j.jtcvs.2013.10.084
  20. Huo Y., Schoenbauer R., Richter S., et al. Atrial arrhythmias following surgical AF ablation: electrophysiological findings, ablation strategies, and clinical outcome. J Cardiovasc Electrophysiol. 2014;25(7):725–738. doi: 10.1111/jce.12406
  21. Cox J.L., Churyla A., Malaisrie S.C., et al. A hybrid maze procedure for long-standing persistent atrial fibrillation. Ann Thorac Surg. 2019;107(2):610–618. doi: 10.1016/j.athoracsur.2018.06.064

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. Medtronic equipment: а — bipolar ablative device (clamping-electrode) Medtronic Cardioblate Gemini-S; б — cardioblate Generator 68000 RF generator.

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3. Fig. 2. AtriCure equipment: а — bipolar clamping-electrode Isolator EMR2, right; б — bipolar clamping-electrode Isolator EML2, left; в — electrode for linear ablation MLP1; г — radio frequency generator AtriCure.

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4. Fig. 3. Pattern of isolation of the antrum of the pulmonary veins and the posterior wall of the left atrium using Medtronic equipment (а) and AtriCure (б).

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5. Fig. 4. Positioning of the stapler during resection of the left atrium appendage.

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6. Fig. 5. Operative time and time of ablation time in the studied groups (p <0,05).

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Copyright (c) 2022 Zotov A.S., Pidanov O.Y., Osmanov I.S., Troitskiy A.V., Silayev A.A., Sakharov E.R., Sukhotin V.N., Shelest O.O., Khabazov R.I., Timashkov D.A.

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