Harlequin’s face — a rare form of autonomic dysfunction during dissection of the internal carotid artery

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Abstract

A comprehensive examination and dynamic observation of a patient with clinical manifestations of connective tissue dysplasia and dissection of the internal carotid arteries revealed a symptom complex characteristic of Harlequin syndrome. The description of this form of pathology is given for the first time in the national literature. A brief review presents the diagnostic criteria and mechanisms for the development of this rare autonomic dysfunction.

About the authors

Vladimir V. Belopasov

Astrakhan State Medical University

Email: belopasov@yandex.ru
ORCID iD: 0000-0003-0458-0703
SPIN-code: 6089-1321

doctor of medical sciences, professor Head of the Department of Neurology and Neurosurgery with a course of postgraduate education 

Russian Federation, 121, Bakinskaya Street, Astrakhan, 414000

Maria V. Gubanova

Research Center for Neurology

Email: m.v.gubanova@yandex.ru
SPIN-code: 9341-4397

neurologist of the 3 neurological department 

Russian Federation, 125367, Moscow, Volokolamskoye sh., 80

Anastasia V. Belopasova

Research Center for Neurology

Author for correspondence.
Email: mastusha@yandex.ru
ORCID iD: 0000-0003-3124-2443
SPIN-code: 3149-3053

Candidate of Medical Science, Researcher of the 3 neurology department

Russian Federation, 125367, Moscow, Volokolamskoye sh., 80

Ludmila A. Kalashnikova

 Research Center of Neurology

Email: kalashnikovancn@yandex.ru
SPIN-code: 4424-3678

doctor of medical sciences, professor, chief research officer of the 3 neurological department 

Russian Federation, 125367, Moscow, Volokolamskoye sh., 80

Larisa A. Dobrinina

Research Center of Neurology

Email: dobrla@mail.ru
SPIN-code: 2824-8750

doctor of medical sciences, head of the 3 neurological department 

Russian Federation, 125367, Moscow, Volokolamskoye sh., 80,

References

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  2. Калашникова Л.А., Добрынина Л.А., Корепина О.С., и соавт. Анамнестическая головная боль у больных с диссекцией магистральных артерий головы: клинические особенности и механизмы развития // Журнал неврологии и психиатрии им. С.С. Корсакова. — 2018. — Т.118. — №7. — С. 4–11. [Kalashnikova LA, Dobrynina LA, Korepina OS, et al. Anamnestic headache in patients with cervical artery dissection: clinical characteristics and pathogenetic mechanisms. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. 2018;118(7):4–11. (In Russ).]
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  8. Lee DH, Seong JY, Yoon TM, et al. Harlequin syndrome and Horner syndrome after neck schwannoma excision in a pediatric patient: A case report. Medicine (Baltimore). 2017;96(45):e8548. doi: 10.1097/MD.0000000000008548.
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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. MRI of the arteries of the neck, T1VI Fat-Sat without contrast enhancement and 3D-TOF MRA patient L., 45 years old, with dissection of the right ICA

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3. Fig. 2. The face of the Harlequin

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4. Fig. 3. Vegetative innervation of the face: normal, with denervation [7]

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Copyright (c) 2019 Belopasov V.V., Gubanova M.V., Belopasova A.V., Kalashnikova L.A., Dobrinina L.A.

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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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