ANALYSIS OF FATAL CASES OF MELANOMA IN MILITARY PERSONNEL

Melanoma is considered one of the most aggressive tumors, characterized by a rapid course and multiple metastasis. Many issues of etiopathogenesis, diagnosis and treatment of skin melanoma remain relevant, insufficiently studied, therefore, the study of the tumor among scientists of the whole world is of great scientific and practical interest. It’s useful in the world of oncological diseases of the skin, among which melanoma is 3-5%, and continue to grow. Melanoma has an aggressive course, the average 5-year survival rate at the late stages of tumor development is 18%. The average annual rate of growth in the incidence of melanoma in the world is about 5%, this indicator is considered one of the highest high numbers of malignant tumors of the earth. The purpose of the study: to study cases of fatal outcomes among military personnel with skin melanoma, using general scientific methods, to identify the alleged causes of the disease. The contract servicemen from various districts showed an increase in pigmented skin formation, a change in color and surface against the background of a pigmented nevus, which had existed since childhood or developed de novo, in two cases, the primary focus was not detected. The average age was 42 years. In most cases, surgical excision of the formation was carried out, the diagnosis was established at the II-III-IV stages of malignant melanoma, usually in the presence of regional and distant metastases. Chemotherapy, radiation and hormone therapy did not improve the condition, and myelotoxicity and the progression of metastatic damage to internal organs, more often the brain, led to deterioration, severe anemia and multiple organ failure, which was the direct cause of deaths.

military personnel, melanoma, predictors, nevi, stage, metastases, cause of death