PHYSIOLOGICAL AND REPARATIVE REGENERATION OF HAIR ROOT EPITELIOCYTES

The physiological and reparative regeneration of epithelial cells of human and mouse hair roots was studied at the level of light microscopy. Comparison and analysis of longitudinal and transverse sections of hair roots at different levels. Reactive cell changes in the area of the hair follicle were identified and described. The cyclic activity of hair growth and sources of cambial cells of hair follicles were studied. At the stages of catagen and telogen (stages of stunting and dormancy during physiological regeneration), reduction of cells of the internal root sheath is noted. During reparative regeneration, only reactive changes in these cells were observed. During physiological regeneration at the catagen stage, mitoses of the cells of the external epithelial sheath are usually localized, and during reparative regeneration they are visible around the entire circumference of the hair follicle. It was shown that the state of epithelial cells of hair roots, especially cell of hair matrix, allows more accurate orientation within the perinecrotic area of the wound on the skin surface.

hair root, hair follicle, hair matrix, dermal papilla, external and internal root sheath, semi-thin sections, reactive changes