REGENERATIVE HISTION OF GRANULATION TISSUE

Cell-differential analysis of a reactively changed connective tissue of the dermis, called granulation tissue, is formed in the phase of proliferation and differentiation of regenerative histogenesis. The experimental preparations of skin sections were studied on the 6th day after the application of a musculoskeletal wound at a light-optical level. The development of the problem of the regulation of the processes of reparative regeneration of connective tissue can be transferred to a new, higher level of targeted stimulation, provided that there is a deep knowledge of inter-differential interactions. New morphometric data on the mechanisms of interaction between cells and intercellular substance of granulation tissue are obtained. The morphological and functional characteristics of cell differentials of granulation tissue were revealed and described: fibroblastic, fibroclastic, mast cell differon, macrophages and structures of angioblastic differon.

muscle and skin wound, regeneration, regenerative histion, granulation tissue, myofibroblasts, macrophages, mast cells, reparative histogenesis