Chorionic bump: ultrasound predictor of adverse pregnancy outcome

Cover Page

Cite item

Full Text

Abstract

For the first time R. Harris et al. in 2006 a chorionic bump was described, detected by ultrasound examination in the first trimester of pregnancy, having characteristic ultrasound signs and localization. Modern knowledge about the etiology and clinical significance of chorionic bump for predicting the outcome of pregnancy is insufficient and contradictory. Inconsistency of the data may be due to the rarity of occurrence, a small sample of the studied groups, the lack of histopathological studies. Among doctors who make ultrasound investigations there is a low awareness of chorionic bump and as a result an erroneous interpretation of sonography data. Nevertheless, there is more and more evidence that this sign is a predictor of an adverse outcome of pregnancy. Doctors who make ultrasound investigations in the first trimester of pregnancy should be aware of the chorionic bump and be able to differentiate it with other pathological conditions. If a chorionic bump is detected, ultrasound examination in dynamics should be recommended. Based on the study of domestic and foreign literature, this scientific review presents modern ideas about the pathomorphology of chorionic bump, informations about significance in terms of predicting the outcome of pregnancy, and the main aspects of ultrasound diagnostics and differential diagnosis of this pathology.

About the authors

Igor S. Zheleznyak

Military Medical Academy

Email: igzh@bk.ru
ORCID iD: 0000-0001-7383-512X
SPIN-code: 1450-5053

M.D., D.Sc. (Medicine), Professor

Russian Federation, Saint Petersburg

Vladimir V. Ryazanov

Military Medical Academy; Saint Petersburg State Pediatric Medical University

Email: 79219501454@yandex.ru
ORCID iD: 0000-0002-0037-2854
SPIN-code: 2794-6820

M.D., D.Sc. (Medicine)

Russian Federation, Saint Petersburg; Saint Petersburg

Gulnaz K. Sadykova

Military Medical Academy; Saint Petersburg State Pediatric Medical University

Email: kokonya1980@mail.ru
ORCID iD: 0000-0002-6791-518X
SPIN-code: 3115-7430

M.D., Ph.D. (Medicine)

Russian Federation, Saint Petersburg; Saint Petersburg

Igor V. Boykov

Military Medical Academy

Email: qwertycooolt@mail.ru
ORCID iD: 0000-0001-9594-9822
SPIN-code: 1453-8437

M.D., D.Sc. (Medicine); Professor

Russian Federation, Saint Petersburg

Sergey G. Glebov

Saint Petersburg State Pediatric Medical University

Email: sergey1990glebov@mail.ru
ORCID iD: 0009-0006-0446-5050

3rd year student

Russian Federation, Saint Petersburg

Natalya Yu. Kuznetsova

Scientific Research Institute of Pulmonology

Email: kznnataly@mail.ru
ORCID iD: 0009-0005-1057-5048

M.D., Ph.D. (Medicine)

Russian Federation, Moscow

Anastasiya Ya. Latysheva

Military Medical Academy

Email: vaska.petrova@yandex.ru
ORCID iD: 0000-0003-3677-8765
SPIN-code: 6793-1985

M.D., Ph.D. (Medicine)

Russian Federation, Saint Petersburg

Roman A. Postanogov

Saint Petersburg State Pediatric Medical University

Author for correspondence.
Email: r.a.postanogov@yandex.ru
ORCID iD: 0000-0002-0523-9411
SPIN-code: 8686-1597

radiologist; address

Russian Federation, Saint Petersburg

References

  1. Harris RD, Couto C, Karpovsky C, et al. The chorionic bump: a first-trimester pregnancy sonographic finding associated with a guarded prognosis. J Ultrasound Med. 2006;25(6):757–763. doi: 10.7863/jum.2006.25.6.757
  2. Arleo EK, Troiano RN. Chorionic bump on first-trimester sonography: not necessarily a poor prognostic indicator for pregnancy. J Ultrasound Med. 2015;34(1):137–142. doi: 10.7863/ultra.34.1.137
  3. Galleguillos C, Sepulveda W. Chorionic bump: Progression to a subamniotic hematoma. J Ultrasound Med. 2022;30(Pt 1):90–93. doi: 10.1177/1742271X211008565
  4. Yousaf A, Tayyab A, Anil MSU, et al. Chorionic Bump: Radiologic Features and Pregnancy Outcomes. Cureus. 2020;12(11): e11480. doi: 10.7759/cureus.11480
  5. Silva MC, Sepulveda-Martinez A, Guinez R, et al. Chorionic bump: an early ultras und marker for adverse obstetric outcome. Gynecol Obstet Invest. 2019;84(5):237–241. doi: 10.1159/000493477
  6. Altynnik NA, Medvedev MV, Voityuk EG. Chorial protrusion: analysis of 16 observations and literature review. Prenatal diagnostics. 2018;17(2):116–121. (In Russ.)
  7. Sana Y, Appiah A, Davison A, et al. Clinical significance of first-trimester chorionic bumps: a matched case-control study. Ultrasound Obstet Gynecol. 2013;42(5):585–589. doi: 10.1002/uog.12528
  8. Younesi L, Shahnazari R. Chorionic Bump in First-trimester Sonography. J Ultrasound Med. 2017;25(Pt 4):221–226. doi: 10.1016/j.jmu.2017.04.004
  9. Sepulveda W. Chorionic bump at 11 to 13 weeks’ gestation: Prevalence and clinical significance. Prenat Diagn. 2019;39(Pt 6): 471–476. doi: 10.1002/pd.5454
  10. Lu Y, Wu Y, Huang F, Ren M. A single-center retrospective study of the clinical significance of chorionic bump at early stage of gestation. Am J Reprod Immunol. 2021;85(3):e13346. doi: 10.1111/aji.13346
  11. Wax JR, Cartin A, Litton C, et al. First-trimester chorionic bump —Association with fetal aneuploidy in a high-risk population. J Clin Ultrasound. 2017;45(1):3–7. doi: 10.1002/jcu.22417
  12. Baalmann CG, Galgano SJ, Pietryga JA, et al. A Case of a Chorionic Bump: New Sonographic-Histopathologic Findings With Review of the Literature. J Ultrasound Med. 2017;36(Pt 9):1968–1970. doi: 10.1002/jum.14240.
  13. Carvalho RS, Osório M, Brito C, et al. Chorionic bump in a pregnant patient with a history of infertility. BMJ Case Rep. 2018;2018: bcr2018225091. doi: 10.1136/bcr-2018-225091
  14. Woodward PJ, Kennedy A, Sohaey R. Diagnosis Imaging: Obstetrics. Amsterdam: Elsevier Science; 2016. 1240 p.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Rice. 1. Transvaginal sonograms (a, b) visualize a solitary chorionic protrusion (arrows) of the solid echostructure, uniformly increased echogenicity, comparable in echogenicity to the chorion

Download (104KB)
3. Rice. 2. On serial transvaginal sonograms, the yolk sac is visualized (a, dotted arrow), embryo (b, dotted arrow), two CVs partially (a and b, solid arrows) and completely (c, solid arrows), hypoechoic in the central part with a peripheral hyperechoic rim

Download (182KB)

Copyright (c) 2023 Eco-Vector

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).