The preoperative assessment of the stroke risk in oncosurgery
- Authors: Tsygan N.V.1,2, Yakovleva V.A.1,3, Fufaev E.E.1, Ismail R. Eleskhanov I.R.4, Sapozhnikov K.V.1, Nechiporuk V.M.1, Ilya I. Dzidzava I.I.1, Litvinenko I.V.5
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Affiliations:
- Military Medical Academy
- B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Centre "Kurchatov Institute"
- Raisa Gorbacheva Memorial Institute for Children Hematology and Transplantation
- 1477 Naval Clinical Hospital of the Pacific Fleet, Branch № 2
- Военно-медицинская академия
- Issue: Vol 41, No 4 (2022)
- Pages: 365-370
- Section: Original articles
- URL: https://journals.rcsi.science/RMMArep/article/view/111863
- DOI: https://doi.org/10.17816/rmmar111863
- ID: 111863
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Abstract
AIM: of the research was to develop a mathematical model for the preoperative assessing of the stroke risk in surgical operations for malignant neoplasms of the chest and abdomen for the early identification of high-risk patients optimization of diagnostics and enhancing the efficacy of personalized preventive measures.
MATERIALS AND METHODS: 47 cases of perioperative stroke according to archived case histories patients with malignant neoplasms of various localization — retrospective analysis anamnesis of life and underlying disease, analysis of clinical and laboratory examination data, analysis of parameters associated with surgery and anesthetic aid, analysis of the clinical and neuroimaging picture of perioperative stroke; 102 patients who underwent elective surgery for the malignant neoplasm of the chest or abdomen — perioperative dynamic neurological support collection of anamnesis of life and disease, analysis of clinical and laboratory examination data, neurological examination with NIHSS and mRankin scores, neuropsychological testing using MoCA and FAB.
RESULTS: Risk factors for perioperative stroke in oncosurgical patients, as well as cerebroprotective factors have been established. The valid mathematical model was developed for assessing of the likelihood of perioperative stroke in the surgical treatment of malignant neoplasms of the chest and abdomen with a predictive power of 85.4%, sensitivity of 77%, and specificity of 87%.
CONCLUSION: The proposed mathematical model allows preoperatively assess the risk of perioperative stroke in percentage (according to the anamnesis and medical records data) and identify the group of high-risk patients.
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##article.viewOnOriginalSite##About the authors
Nikolay V. Tsygan
Military Medical Academy; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Centre "Kurchatov Institute"
Email: 1860n@mail.ru
ORCID iD: 0000-0002-5881-2242
SPIN-code: 1006-2845
Scopus Author ID: 37066611200
ResearcherId: H-9132-2016
M.D., D.Sc. (Medicine), Associate Professor
Russian Federation, Saint Petersburg; Gatchina, Leningrad regionVictoria A. Yakovleva
Military Medical Academy; Raisa Gorbacheva Memorial Institute for Children Hematology and Transplantation
Email: 24ro80@gmail.com
ORCID iD: 0000-0002-9839-3169
SPIN-code: 6158-5505
Scopus Author ID: 56941569100
ResearcherId: AAZ-6393-2021
Russian Federation, Saint Petersburg; Saint Petersburg
Evgeniy E. Fufaev
Military Medical Academy
Email: Fufaev.jj@gmail.com
SPIN-code: 5758-2364
M.D., Ph.D. (Medicine), Associate Professor
Russian Federation, Saint PetersburgIsmail R. Ismail R. Eleskhanov
1477 Naval Clinical Hospital of the Pacific Fleet, Branch № 2
Email: eleshanov_ir@mail.ru
SPIN-code: 7413-6348
Russian Federation, Petropavlovsk-Kamchatsky
Kirill V. Sapozhnikov
Military Medical Academy
Email: marinheira@rambler.ru
ORCID iD: 0000-0002-2476-7666
SPIN-code: 2707-0339
Scopus Author ID: 57200810332
ResearcherId: ААЕ-3453-2022
Russian Federation, Saint Petersburg
Vasilii M. Nechiporuk
Military Medical Academy
Email: me1225@bk.ru
SPIN-code: 2437-4331
Russian Federation, Saint Petersburg
Ilya I. Ilya I. Dzidzava
Military Medical Academy
Email: dzidzava@mail.ru
ORCID iD: 0000-0002-5860-3053
SPIN-code: 7336-9643
Scopus Author ID: 8901380100
ResearcherId: Q-1992-2016
M.D., D.Sc. (Medicine), Associate Professor
Russian Federation, Saint PetersburgIgor V. Litvinenko
Военно-медицинская академия
Author for correspondence.
Email: litvinenkoiv@rambler.ru
ORCID iD: 0000-0001-8988-3011
SPIN-code: 6112-2792
Scopus Author ID: 35734354000
ResearcherId: F-9120-2013
M.D., D.Sc. (Medicine), Professor
Russian Federation, Санкт-ПетербургReferences
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