Changes in Mental and Physical Status and Potential Treatment for Patients with Post-COVID-19 Chronic Heart Failure
- 作者: Nurmakhanova Z.M.1, Zhankalova Z.M.1, Abdugulova G.Z.1, Abdykulova A.B.1, Gabdulina G.H.1, Tazhieva A.E.1, Khabizhanova V.B.1, Omarova I.S.1, Ensegenova Z.Z.1, Yerenchina E.R.1, Kasymova R.N.1, Matchanova M.S.1, Erlepessova A.T.1, Yessirkepova A.Z.1, Zhaparkulova M.T.1, Kushimbaeva K.S.1, Tuleutayeva S.A.1
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隶属关系:
- Asfendiyarov Kazakh National Medical University
- 期: 卷 29, 编号 2 (2025)
- 页面: 51-62
- 栏目: Original study article
- URL: https://journals.rcsi.science/RFD/article/view/313555
- DOI: https://doi.org/10.17816/RFD640797
- EDN: https://elibrary.ru/SYIHXO
- ID: 313555
如何引用文章
详细
BACKGROUND: Coronavirus infection can negatively impact the mental and physical status of patients with chronic heart failure, exacerbating anxiety and depressive symptoms. These changes should be recognized and addressed promptly.
AIM: The study aimed to evaluate the impact of COVID-19 on the mental and physical status of patients with chronic heart failure who were eligible for treatment in primary care settings.
METHODS: The study included patients with chronic heart failure of various origins with or without a history of COVID-19. The physical and mental health of all patients was evaluated using three scales: the Sheehan Patient-Rated Anxiety Scale, the Beck Depression Inventory, and the Social Adaptation Self-Evaluation Scale. Eligible patients with COVID-19 were prescribed sertraline, a selective serotonin reuptake inhibitor antidepressant, based on results of a psychometric evaluation.
RESULTS: Sertraline is shown to significantly improve anxiety disorder, particularly severe cases, in patients with chronic heart failure who have recovered from COVID-19. Sertraline was found to be even more clinically effective in the treatment of depression; it improved depressive symptoms in all study groups. Sertraline was found to affect cardiovascular parameters in patients with chronic heart failure after COVID-19. Sertraline decreased heart rate, thereby improving the course of chronic heart failure. In addition, the ejection fraction remained virtually unchanged in the short term, which indicates the efficacy and safety of sertraline. This supports the recommendation to add sertraline to the combined therapy for this patient group.
CONCLUSION: The study confirms the significant impact of COVID-19 on the physical and mental status of patients with chronic heart failure. However, the agents used to treat these conditions may affect the cardiovascular system. Patients require a comprehensive treatment strategy that includes support for mental and physical health.
作者简介
Zhannat Nurmakhanova
Asfendiyarov Kazakh National Medical University
Email: zhanna12932@mil.ru
ORCID iD: 0000-0002-6528-7060
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyZulfiya Zhankalova
Asfendiyarov Kazakh National Medical University
Email: zulfiya-zhankalo@mail.ru
ORCID iD: 0000-0002-5122-4130
MD, Dr. Sci. (Medicine)
哈萨克斯坦, AlmatyGulbanu Abdugulova
Asfendiyarov Kazakh National Medical University
Email: a.gulbany@mail.ru
ORCID iD: 0000-0001-8832-9705
哈萨克斯坦, Almaty
Akmaral Abdykulova
Asfendiyarov Kazakh National Medical University
Email: akmaral_abd@mail.ru
ORCID iD: 0000-0002-0330-6764
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyGulzhan Gabdulina
Asfendiyarov Kazakh National Medical University
Email: gabdulina.g@kaznmu.kz
ORCID iD: 0000-0001-5536-6227
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyAigul Tazhieva
Asfendiyarov Kazakh National Medical University
Email: a.tazhiyeva@mail.ru
ORCID iD: 0000-0002-3674-0321
MD, Dr. Sci. (Medicine)
哈萨克斯坦, AlmatyVenera Khabizhanova
Asfendiyarov Kazakh National Medical University
Email: habizhanova.v@kaznmu.kz
ORCID iD: 0000-0002-7488-0173
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyIndira Omarova
Asfendiyarov Kazakh National Medical University
Email: indiraomarova.kz1989@gmail.com
ORCID iD: 0000-0001-8312-0558
哈萨克斯坦, Almaty
Zoya Ensegenova
Asfendiyarov Kazakh National Medical University
Email: zoyazhar@mail.ru
ORCID iD: 0009-0008-9934-9523
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyElmira Yerenchina
Asfendiyarov Kazakh National Medical University
Email: elmira_er@mail.ru
ORCID iD: 0000-0002-4318-2946
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyRaushan Kasymova
Asfendiyarov Kazakh National Medical University
Email: rau-nur@mail.ru
ORCID iD: 0000-0002-0845-9794
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyMarzhan Matchanova
Asfendiyarov Kazakh National Medical University
Email: maka130773@mail.ru
ORCID iD: 0009-0002-6979-899X
MD, Cand. Sci. (Medicine)
哈萨克斯坦, AlmatyAigul Erlepessova
Asfendiyarov Kazakh National Medical University
Email: aigul.a_84@mail.ru
ORCID iD: 0009-0009-6882-3605
哈萨克斯坦, Almaty
Aizhamal Yessirkepova
Asfendiyarov Kazakh National Medical University
编辑信件的主要联系方式.
Email: aizhamal-65@mail.ru
ORCID iD: 0000-0003-2991-8651
哈萨克斯坦, Almaty
Madina Zhaparkulova
Asfendiyarov Kazakh National Medical University
Email: mediksun@mail.ru
ORCID iD: 0009-0009-7795-0657
哈萨克斯坦, Almaty
Kaldygul Kushimbaeva
Asfendiyarov Kazakh National Medical University
Email: kalda77@mail.ru
ORCID iD: 0009-0000-8994-710X
哈萨克斯坦, Almaty
Svetlana Tuleutayeva
Asfendiyarov Kazakh National Medical University
Email: maxataul@mail.ru
ORCID iD: 0000-0002-9287-0454
哈萨克斯坦, Almaty
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