Email this article Smoking and lung cancer (clinical and epidemiological study)
- Authors: Yurkova Y.P.1, Merabishvili V.M.1
-
Affiliations:
- N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation
- Issue: Vol 4, No 2 (2022)
- Pages: 36-42
- Section: Biomedical Sciences
- URL: https://journals.rcsi.science/PharmForm/article/view/232615
- DOI: https://doi.org/10.17816/phf108772
- ID: 232615
Cite item
Full Text
Abstract
Tobacco smoke is one of the dangerous exogenous factors contributing to the emergence of chronic non–communicable diseases and, first of all, malignant tumors.
Purpose. On the basis of the hospital cancer registry created at the N.N. Petrov National Medical Research Center of Oncology (N.N. Petrov NMRC of Oncology), to analyze the differences in the specific weights of the risk of exposure to the smoking factor on cancer patients treated in the hospital with various oncopathologies. At the population level, to consider the dynamics of morbidity and mortality of the population of Russia, the North-Western Federal District (NWFD) and St. Petersburg of lung cancer patients, taking into account the impact of the coronavirus pandemic.
The material of the study is the created database (DB) of the hospital and population cancer registry, working according to international standards and statistical reference books of the P.A. Herzen Moscow Research Institute of Oncology (P.A. Herzen Institute of Oncology) and the N.N. Petrov NMRC of Oncology, questioning of patients in the hospital.
Results. Of the 47,356 patients treated at the center, 9201 or 19.4% abused smoking. The highest percentage of smokers was found among patients with laryngeal cancer (C32) – 66.67%, esophageal cancer (C15) – 53.20% and lung cancer (C33,34) – 51.08. The lowest proportion of smokers among patients diagnosed with uterine body cancer (C54) – 8.8% and breast (C50) – 10.1%. It was found that 52.01% of smokers smoked more than half, up to one pack of cigarettes a day.
Conclusions. Thus, the study proved a direct link between the smoking factor and the development of malignant tumors. It was found that more than 50% of patients with lung cancer are smokers. The proportion of smoking patients for other nosologies is significantly less, with the exception of laryngeal (C32) and esophageal (C15). We also noted an increase in the number of women who smoke both in the whole group of patients and in the group of patients diagnosed with lung cancer.
Full Text
##article.viewOnOriginalSite##About the authors
Yulia P. Yurkova
N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: yurkova@niioncologii.ru
ORCID iD: 0000-0002-5448-8115
SPIN-code: 4697-6433
doctor statistician, Department of organization and quality control of medical care
Russian Federation, Saint PetersburgVakhtang M. Merabishvili
N. N. Petrov National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation
Email: MVM@niioncologii.ru
ORCID iD: 0000-0002-1521-455X
SPIN-code: 5705-6327
Doctor of Medicine (MD), Professor, Chief of the Oncological Statistics Scientific Laboratory, Chairman of the Scientific-Methodological Council on the Development of Information Systems of Cancer Control of the Northwestern Federal District; Head of the Population-based Cancer Registry of the Northwestern Federal District of the Russian Federation
Russian Federation, Saint PetersburgReferences
- Zaridze D. G., Mukeria A. F. Prevention of smoking-associated forms of cancer: harm reduction concept. Prakticheskaya onkologiya = Practical oncology. 2020;21(3):197-229. https://doi.org/10.31917/2103197. (In Russ.).
- Drope J., Silluger N., Caln Z., et al., eds. The Tobacco Atlas. Atlanta: American cancer society and vital strategies; 2018. 58 p.
- Zdorovyy obraz zhizni: monitoring. WCIOM. URL: https://wciom.ru/analytical-reviews/analiticheskii-obzor/zdorovyj-obraz-zhizni-monitoring. (In Russ.).
- Sakharova G. M., Antonov N. S., Salagay O. O. Global survey of the adult population on tobacco consumption in the Russian Federation: GATS 2009 and GATS 2016. Narkologiya = Narcology. 2017;16(7):8-12. (In Russ.).
- Sakharova G. M., Antonov N. S., Salagay O. O. Monitoring the prevalence of tobacco consumption in the Russian Federation: global adult tobacco surveys in 2009 and 2016. Meditsina = Medicine. 2017;(2):64-72. (In Russ.).
- Merabishvili V. M., Belyaev A. M., Shcherbakov A. M., eds. Malignant tumors in the NorthWest Federal Region of Russia (morbidity, mortality, prevalence rate, survival). Express-information. 5th issue. Guidelines for physicians. Saint Petersburg: T8 Print; 2020. 236 p. (In Russ.).
- Federal State Statistics Service. URL: https://rosstat.gov.ru/. (In Russ.).
- Kurenie i rynok sigaret v Rossii. Zdrav.Expert. URL: https://zdrav.expert/index.php. (In Russ.).
- Perekrest V. Tabachnye kompanii pokidayut Rossiyu medlenno i pechal'no: chto teper' budet s sigaretami i tsenami na nikh. Komsomolskaya Pravda. 2022. URL: https://www.kp.ru/daily/27393/4588532. (In Russ.).
- Kaprin A. D., Starinsky V. V., Shakhzadova A. O., eds. Zlokachestvennye novoobrazovaniya v Rossii v 2020 godu (zabolevaemost' i smertnost'). Moscow: P.A. Herzen Moscow State Medical Research Institute - branch of the NMRRC of the Ministry of Health of the Russian Federation; 2021. 252 p. (In Russ.).
- Doll R., Peto R., Boreham J., et al. Mortality in relation to smoking: 50 years’ observations on male British doctors. Br. Med. J. 2004;328(7455):1519-1528. https://doi.org/10.1136/bmj.38142.554479.AE.
Supplementary files
