大脑海绵状畸形及其治疗的现代观点

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由于现代神经影像学方法的发展，近年来大脑海绵状畸形已成为越来越可检测的病理。尽管在大多数情况下病程的性质是良性的，但这些形成可导致惊厥综合征和严重神经系统疾病的发展。基本上临床症状的原因是洞穴结构和大脑周围实质的出血。大脑海绵状畸形患者的管理策略的选择取决于畸形的类型，其大小，定位，反复出血的存在和临床情况。

这篇文献综述致力于海绵体畸形的现代治疗方法。我们分析治疗脑海绵状畸形的主要方法，特别是手术治疗。无法手术干预的时候，在大脑功能显着区域的病灶深度定位的情况下，其特征在于并发症的最大风险，放射治疗的替代方法是如立体定向放射外。同时审查立体定向放射外科治疗的可能性，有效性和安全性，使用质子治疗治疗海绵体畸形。揭示了治疗海绵体畸形的辐射方法的优点。

作者简介

Elena N. Girya

Sklifosovsky Research Institute for Emergency Medicine

编辑信件的主要联系方式.
Email: mishka_77@list.ru
ORCID iD: 0000-0001-5875-1489
SPIN 代码: 4793-7748

Radiologist of Radiosurgery Department
俄罗斯联邦, 3 Bol’shaya Sukharevskaya ploshcad, 129010 Moscow

Valentin V. Sinitsyn

Lomonosov Moscow State University

Email: vsini@mail.ru
ORCID iD: 0000-0002-5649-2193
SPIN 代码: 8449-6590

MD, Dr. Sci. (Med.), Professor, Head of the Department of Radiation Diagnostics, Medical Research and Education Center

俄罗斯联邦, Moscow

Alexey S. Tokarev

Sklifosovsky Research Institute for Emergency Medicine; Moscow Health Department

Email: alex_am_00@mail.ru
ORCID iD: 0000-0002-8415-5602
SPIN 代码: 1608-0630

MD, Cand. Sci. (Med.), Deputy Head of Moscow Health Department, neurosurgeon of Radiosurgery Department

俄罗斯联邦, 3 Bol’shaya Sukharevskaya ploshcad, 129010, Moscow; Moscow

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2. 图 1骨膜海绵状血管瘤质子放射外科手术计划： 治疗前和治疗后 3 个月（海绵状血管瘤完全吸收）的 MRI 对比。

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