Email this article A clinical example of the effect of latent infection and chronic inflammation on urination disorders in a 12-year-old child without organic pathology. Case report
- Authors: Bozhendaev T.L.1,2, Simonova A.V.3,4, Guseva N.B.1,2,5, Nikitin S.S.6,7
-
Affiliations:
- Pirogov Russian National Research Medical University
- Speransky Children's City Clinical Hospital №9
- Vladimirsky Moscow Regional Research Clinical Institute
- Academy of Medical and Technical Sciences of the Eurasian Association of Medical and Ecological Technologies
- Russian Medical Academy of Continuing Professional Education
- Petrozavodsk State University
- Grigovich Children's Republican Hospital
- Issue: No 1 (2024)
- Pages: 64-69
- Section: Articles
- URL: https://journals.rcsi.science/2658-6630/article/view/256719
- DOI: https://doi.org/10.26442/26586630.2024.1.202775
- ID: 256719
Cite item
Full Text
Abstract
Bladder dysfunctions of inorganic origin in childhood are found in 40% of visits to the doctor about urination disorders. In the practice of pediatricians, there are patients who do not respond well to basic treatment, and urination disorders persist for several years. Such patients are included in the group of frequently ill children, have frequent recurrences of urinary tract infections. This publication describes the conducted microbiological studies of patients by the method of chromatography-mass spectrometry of microbial markers. The expected results of latent microbial agents were obtained in the discharge from the pharynx, the contents of the intestinal lumen, and urinary sediment. The presence of infection in the surveyed regions contributed to the maintenance of a chronic inflammatory process. The conducted antimicrobial treatment contributed to the relief of inflammation and potentiated the basic therapy, which contributed to the effective correction of urinary disorders of inorganic origin in children.
Full Text
##article.viewOnOriginalSite##About the authors
Timofei L. Bozhendaev
Pirogov Russian National Research Medical University; Speransky Children's City Clinical Hospital №9
Author for correspondence.
Email: dr.bozhendaev@gmail.com
ORCID iD: 0000-0002-8819-0771
Cand. Sci. (Med.)
Russian Federation, Moscow; Moscow
Albina V. Simonova
Vladimirsky Moscow Regional Research Clinical Institute; Academy of Medical and Technical Sciences of the Eurasian Association of Medical and Ecological Technologies
Email: medlabnews@mail.ru
ORCID iD: 0000-0001-9289-4010
Sci. (Med.), Prof.
Russian Federation, Moscow; MoscowNatalia B. Guseva
Pirogov Russian National Research Medical University; Speransky Children's City Clinical Hospital №9; Russian Medical Academy of Continuing Professional Education
Email: guseva-n-b@yandex.ru
ORCID iD: 0000-0002-1583-1769
Sci. (Med.)
Russian Federation, Moscow; Moscow; MoscowSergei S. Nikitin
Petrozavodsk State University; Grigovich Children's Republican Hospital
Email: ssnikitin@yandex.ru
ORCID iD: 0000-0002-4920-1722
Sci. (Med.)
Russian Federation, Petrozavodsk; PetrozavodskReferences
- Гусева Н.Б., Никитин С.С. Нейрофизиологические аспекты расстройств мочеиспускания неорганического генеза у детей, основные принципы диагностики и лечения. Педиатрия им. Г.Н. Сперанского. 2017;96(5):1137-43 [Guseva NB, Nikitin SS. Neurophysiological aspects of urination disorders of inorganic genesis in children, main principles of diagnostics and treatment. Pediatria n.a. G.N. Speransky. 2017;96(5):1137-43 (in Russian)].
- Урсова Н.И. Особенности формирования микробиоценоза у грудных детей и дисбактериоз кишечника. Педиатрия. Consilium Medicum. 2005;7(2):56-9 [ Ursova NI. Features of microbiocenosis formation in infants and intestinal dysbacteriosis. Pediatrics. Consilium Medicum. 2005;7(2):56-9 (in Russian)].
- Епишина И.В., Буданова Е.В. Роль микробиоты человека в развитии нейродегенеративных заболеваний. Журнал неврологии и психиатрии им. С.С. Корсакова. 2022;122(10):57-65 [Epishina IV, Budanova EV. A role of human microbiota in the development of neurodegenerative diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(10):5765 (in Russian)]. doi: 10.17116/jnevro202212210157
- Николаева И.В., Царегородцев А.Д., Шайхиева Г.С. Формирование кишечной микробиоты ребенка и факторы, влияющие на этот процесс. Российский вестник перинатологии и педиатрии. 2018;63(3):13-8 [Nikolaeva IV, Tsaregorodtsev AD, Shaikhieva GS. Formation of the intestinal microbiota if children and the factors that influence this process. Ros Vestn Perinatol i Pediatr. 2018;63(3):13-8 (in Russian)]. doi: 10.21508/1027-4065-2018-63-3-13-18
- Медведев Ю.В., Толстой А.Д. Гипоксия свободные радикалы в развитии патологических состояний организма. М.: Терра-Календер и промоушн, 2000 [Medvedev IuV, Tolstoi AD. Gipoksiia svobodnye radikaly v razvitii patologicheskikh sostoianii organizma. Moscow: Terra-Kalender i promoushn, 2000 (in Russian)].
- Божендаев Т.Л., Гусева Н.Б., Крапивкин А.И., Гаткин Е.Я. Подход к выбору методов коррекции нейрогенной дисфункции мочевого пузыря у детей. Педиатрия. Consilium Medicum. 2022;2:180-4 [Bozhendaev TL, Guseva NB, Gatkin EIa, Krapivkin AI. Approach to the choice of methods for correction of neurogenic bladder dysfunction in children. Pediatrics. Consilium Medicum. 2022;2:180-4 (in Russian)]. doi: 10.26442/26586630.2022.2.201680
- Годков М.А., Осипов Г.А., Федосова Н.Ф., Лядов К.В. Возможности масс-спектрометрии микробных маркеров в лабораторном мониторинге дисбиозов и инфекций. Справочник заведующего КДЛ. 2011;(7):35-44 [Godkov MA, Osipov GA, Fedosova NF, Lyadov KV. Monitoring of infection and disbiosis in laboratory practice by mass-spectrometry of microbial markers. Spravochnik Zaveduyuschego KDL. 2011;(7):35-44 (in Russian)].
- Гострый А.В., Симонова А.В., Михайлова Н.А., и др. Хронический фарингит: этиология, патогенез, лечение. Новые подходы к оценке этиопатогенеза. Архив внутренней медицины. 2019;9(1):32-43 [Gostry AV, Simonova AV, Mikhailova NA, et al. Chronic pharyngitis: Etiology, pathogenesis, treatment. New approaches to the estimation of etiopatogenesis. The Russian Archives of Internal Medicine. 2019;9(1):32-43 (in Russian)]. doi: 10.20514/2226-6704-2019-9-1-32-43
Supplementary files
