Perspectives of peptide hydrolysates in improving the quality of life of patients with varicose vein disease of the lower extremities

varicose vein disease of the lower extremities (VVVD) is a chronic progressive disease that is accompanied by aesthetic and clinical disorders and significantly affects the quality of life of patients. The article aims to evaluate the effect of course monotherapy with hydrolysates of peptides of natural origin (chicken, fish, beef) on the quality of life of patients with chronic venous insufficiency of the lower extremities (CVLI). According to the results, the use of peptide hydrolysates of animal and fish origin reduces the prevalence of complaints of pain, heaviness, and fatigue in the legs, cramps in the calf muscles, and swelling of the ankles and feet in patients with varicose veins of the lower extremities. Assessment of the quality of life by a special questionnaire for patients with chronic venous insufficiency showed a significant improvement after 16 weeks of monotherapy with peptide hydrolysates on all assessment scales: pain, psychological well-being, physical and social disorders. Hydrolysates were characterized by 100% tolerability; the therapeutic effect was expressed already after 8 weeks of course intake and increased as the treatment continued. Peptide hydrolysates are the first systems of restorative low-molecular nutrition and nutritional support of the body in Russia, produced by the Russian company Sofos Protein Biotechnologies from natural domestic animal raw materials and including a wide profile of proteinogenic amino acids that perform a structural function in the formation of proteins.

varicose disease, varicose veins, chronic venous insufficiency, quality of life, peptides, hydrolysates, amino acids, protein hydrolysates