Peptide hydrolysates and quality of life in migraine patients: long-term effects and prospects for improvement (clinical case series)

migraine is a common chronic disease with paroxysmal headaches and focal neurological disorders, which significantly worsens the quality of life. Oxidative stress is the most common factor underlying migraine triggers. The article presents a series of clinical cases of chronic migraine treatment, including resistant to therapy, with peptide hydrolysates of animal and fish origin. According to the patients' results, the use of peptide hydrolysates can be indicated both in standard cases, with mild and moderate manifestations of chronic migraine, and in cases of refractoriness to standard methods of therapy, due to their pronounced antioxidant activity of hydrolysates. Patients observed an increase in the quality of life with short-term use, and with regular use for 6 months or more, a persistent therapeutic effect was observed. Peptide protein hydrolysates are the first systems of restorative low-molecular nutrition and nutritional support of the body in Russia, produced by the Russian company Sophos Protein Biotechnology from natural domestic animal raw materials. Peptide hydrolysates contain a wide range of proteinogenic amino acids that perform a structural function in the formation of proteins: glycine, alanine, proline, serine, aspartic acid, glutamic acid, glutamine, arginine, histidine, tyrosine, including 7 of the 8 essential ones – valine, isoleucine, leucine, threonine, methionine, lysine, phenylalanine.

migraine, peptides, hydrolysates, amino acids, oxidative stress, protein hydrolysates