Ways and Methods for Controlling Biomolecular Structures Using Magnetic Nanoparticles Activated by an Alternating Magnetic Field


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详细

Functionalized magnetic nanoparticles (MNPs) controlled by an external magnetic field provide a new generation of promising nanobiomedical platform. Due to their ability to locally change the state of a biochemical system through two physical processes—thermal and nanomagnetomechanical—they are already used in experiments on targeted drug delivery and therapy of oncological diseases. This work considers the peculiarities, advantages, and drawbacks of each of these processes and the main parameters of the magnetic field controlling the MNP effect on different biomolecular targets. A brief review and comparative analysis of main experimental studies carried out in the scope of magnetic hyperthermia and nanomagnetomechanical actuation are carried out.

作者简介

Yu. Golovin

Department of Chemistry; Research Institute of Nanotechnologies and Nanomaterials

编辑信件的主要联系方式.
Email: nano@tsutmb.ru
俄罗斯联邦, Moscow, 119991; Tambov, 392000

A. Zhigachev

Research Institute of Nanotechnologies and Nanomaterials

Email: nano@tsutmb.ru
俄罗斯联邦, Tambov, 392000

M. Efremova

Department of Chemistry; National University of Science and Technology MISIS

Email: nano@tsutmb.ru
俄罗斯联邦, Moscow, 119991; Moscow, 119991

A. Majouga

Department of Chemistry; National University of Science and Technology MISIS; Mendeleev University of Chemical Technology of Russia

Email: nano@tsutmb.ru
俄罗斯联邦, Moscow, 119991; Moscow, 119991; Moscow, 125047

A. Kabanov

Department of Chemistry; University of North Carolina at Chapel Hill

Email: nano@tsutmb.ru
俄罗斯联邦, Moscow, 119991; Chapel Hill, NC, 27599

N. Klyachko

Department of Chemistry; University of North Carolina at Chapel Hill

Email: nano@tsutmb.ru
俄罗斯联邦, Moscow, 119991; Chapel Hill, NC, 27599

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