Ways and Methods for Controlling Biomolecular Structures Using Magnetic Nanoparticles Activated by an Alternating Magnetic Field
- Авторы: Golovin Y.I.1,2, Zhigachev A.O.2, Efremova M.V.1,3, Majouga A.G.1,3,4, Kabanov A.V.1,5, Klyachko N.L.1,5
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Учреждения:
- Department of Chemistry
- Research Institute of Nanotechnologies and Nanomaterials
- National University of Science and Technology MISIS
- Mendeleev University of Chemical Technology of Russia
- University of North Carolina at Chapel Hill
- Выпуск: Том 13, № 5-6 (2018)
- Страницы: 295-304
- Раздел: Materials of the Conference “Nanomaterials and Living Systems” (NLS-2018), Kazan, 2018
- URL: https://journals.rcsi.science/2635-1676/article/view/220537
- DOI: https://doi.org/10.1134/S1995078018030072
- ID: 220537
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Аннотация
Functionalized magnetic nanoparticles (MNPs) controlled by an external magnetic field provide a new generation of promising nanobiomedical platform. Due to their ability to locally change the state of a biochemical system through two physical processes—thermal and nanomagnetomechanical—they are already used in experiments on targeted drug delivery and therapy of oncological diseases. This work considers the peculiarities, advantages, and drawbacks of each of these processes and the main parameters of the magnetic field controlling the MNP effect on different biomolecular targets. A brief review and comparative analysis of main experimental studies carried out in the scope of magnetic hyperthermia and nanomagnetomechanical actuation are carried out.
Об авторах
Yu. Golovin
Department of Chemistry; Research Institute of Nanotechnologies and Nanomaterials
Автор, ответственный за переписку.
Email: nano@tsutmb.ru
Россия, Moscow, 119991; Tambov, 392000
A. Zhigachev
Research Institute of Nanotechnologies and Nanomaterials
Email: nano@tsutmb.ru
Россия, Tambov, 392000
M. Efremova
Department of Chemistry; National University of Science and Technology MISIS
Email: nano@tsutmb.ru
Россия, Moscow, 119991; Moscow, 119991
A. Majouga
Department of Chemistry; National University of Science and Technology MISIS; Mendeleev University of Chemical Technology of Russia
Email: nano@tsutmb.ru
Россия, Moscow, 119991; Moscow, 119991; Moscow, 125047
A. Kabanov
Department of Chemistry; University of North Carolina at Chapel Hill
Email: nano@tsutmb.ru
Россия, Moscow, 119991; Chapel Hill, NC, 27599
N. Klyachko
Department of Chemistry; University of North Carolina at Chapel Hill
Email: nano@tsutmb.ru
Россия, Moscow, 119991; Chapel Hill, NC, 27599
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