Effective methods of concentration and purification of omega-3 polyunsaturated fatty acids: a systematic review and prospects


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Abstract

the article is devoted to methods of concentrating and purifying omega-3 polyunsaturated fatty acids (PUFAs). The text discusses methods such as transesterification, urea complexation, chromatographic methods, low-temperature crystallization, supercritical fluid extraction, molecular distillation, and iodolactonization. The aim of the research is to systematize literature data to identify the most effective methods for obtaining purified, concentrated omega-3 PUFAs. The methods include transesterification for converting triglycerides into ethyl esters, urea complexation for separating fatty acids, chromatographic methods for high product purity, low-temperature crystallization for simplicity and cost-effectiveness, supercritical fluid extraction for environmental cleanliness and efficiency, molecular distillation for high selectivity, and iodolactonization for prospective separation of omega-3 acids. The article discusses the advantages and disadvantages of methods for concentrating omega-3 PUFAs. It also considers the prospects for developing effective and economical methods of enriching omega-3 fatty acids to reduce costs and meet future demand for highly purified products.

About the authors

I. A Zhuravlev

Far Eastern Federal University

A. F Bocharnikov

Far Eastern Federal University

E. V Maskin

Far Eastern Federal University

D. D Solodiy

Far Eastern Federal University

P. A Shinkaruk

Far Eastern Federal University

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