Endolaryngeal surgery in treatment of early-stage cancer in supraglottic laryngeal region

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Abstract

Objectives – to improve the results of surgical treatment of patients with T1-T2 stages of cancer in the supraglottic and ventricular region by using endolaryngeal resections.

Material and methods. The study was held in Samara Regional Clinical Oncology Center from 2011 to 2016. We analysed 97 case histories of patients diagnosed with stage 0-I laryngeal cancer. The patients were divided into 2 groups depending on the selected organ-preserving method of surgical treatment. The patients of the control group were subjected to open resection of the larynx (laryngofissure). While the patients of the main group received the endolaryngeal resection using an endoscopic rack, a suspension system, a laryngoscope, hard endoscopes of 0, 30, 45 degrees, as well as electrosurgical cutting and endolaryngeal instruments.

Results. The duration of the operation, blood loss, and bed day number was significantly less in patients of the main group in comparison with the control group. Also, the percentage of common complications in the main group was lower in relation to the control group. The three-year relapse-free and overall survival was not significantly different between the study groups.

Conclusion. According to our observations, the endolaryngeal resections in treatment of the initial stages of laryngeal cancer do not impair the results of treatment and do not significantly affect the survival of this category of patients.

About the authors

V. V. Stadler

Samara State Medical University; Samara Regional Clinical Oncology

Email: Gabriel_002@mail.ru
ORCID iD: 0000-0002-5134-0668

PhD, Associate Professor, Department of Ambulance anesthesiology and resuscitation, IPE; Head of the Anesthesiology and resuscitation Department

Russian Federation, Samara

A. A. Mahonin

Samara State Medical University; Samara Regional Clinical Oncology

Email: Gabriel_002@mail.ru

assistant of the Otorhinolaryngology Department n.a. acad. I.B. Soldatov; the Head of the Department of neck and head tumors

Russian Federation, Samara

A. G. Gabrielyan

Samara State Medical University; Samara Regional Clinical Oncology

Author for correspondence.
Email: Gabriel_002@mail.ru
ORCID iD: 0000-0002-5321-6070

assistant of the Department of Dentistry, IPE, maxillofacial surgeon

Russian Federation, Samara

A. I. Sinotin

Samara Regional Clinical Oncology Center

Email: Gabriel_002@mail.ru
ORCID iD: 0000-0001-9641-2349

oncologist

Russian Federation, Samara

M. А. Postnikov

Samara State Medical University

Email: Gabriel_002@mail.ru
ORCID iD: 0000-0002-2232-8870

PhD, Associate Professor, Head of the Department of Dentistry, IPE

Russian Federation, Samara

T. Yu. Vladimirova

Samara State Medical University

Email: Gabriel_002@mail.ru
ORCID iD: 0000-0001-9797-3172

PhD, Associate Professor, Head of the Otorhinolaryngology Department and Clinic n.a. acad. I.B. Soldatov

Russian Federation, Samara

D. S. Kostin

Samara Regional Clinical Oncology Center

Email: Gabriel_002@mail.ru
ORCID iD: 0000-0001-9797-3172

anesthesiologist-reanimatologist

Russian Federation, Samara

Supplementary files

Supplementary Files
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1. JATS XML
2. Fugure 1. Open resection cord.

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3. Figure 2. Endolaryngeal view before and after resection of vocal fold.

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4. Figure 3. Relapse-free survival in compared groups by Kaplan – Meier estimator.

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5. Figure 4. Overall survival in compared groups by Kaplan – Meier estimator.

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Copyright (c) 2020 Stadler V.V., Mahonin A.A., Gabrielyan A.G., Sinotin A.I., Postnikov M.А., Vladimirova T.Y., Kostin D.S.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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