Quality of life assessment in patients with prostate cancer using the FACT-P questionnaire: linguistic and cultural adaptation of the Russian version

Cover Page

Cite item

Full Text

Abstract

Aim – to perform linguistic and cultural adaptation of the international FACT-P (Functional Assessment of Cancer Therapy – Prostate) questionnaire for Russian-speaking patients with prostate cancer and to evaluate its psychometric properties.

Material and methods. The adaptation process included forward and backward translation, expert review, pilot testing (n = 50), and psychometric validation. Internal consistency was assessed using Cronbach’s alpha coefficient, test/retest reliability via intraclass correlation coefficient (ICC), and construct validity by factor analysis.

Results. The Russian version of FACT-P demonstrated high internal consistency across all subscales (α = 0.78–0.89), excellent test/retest reliability (ICC = 0.91), and construct validity confirmed by factor analysis. All five theoretically defined domains – physical, social, emotional, functional well-being, and prostate cancer-specific symptoms – were reliably reproduced in the sample. Most respondents noted the clarity of the wording and the relevance of the content.

Conclusion. The adapted Russian-language version of the FACT-P questionnaire is a reliable, valid, and clinically significant tool for assessing the quality of life in patients with prostate cancer. It is recommended for use in clinical practice and research.

About the authors

Aleksandr A. Zhuravlev

Granov Russian Research Center of Radiology and Surgical Technologies

Author for correspondence.
Email: alexander.a.zh@yandex.ru
ORCID iD: 0009-0006-9566-1080

Postgraduate Student of the Department of Radiology, Surgery and Oncology

Russian Federation, Saint Petersburg

M. I. Shkolnik

Granov Russian Research Center of Radiology and Surgical Technologies

Email: shkolnik_phd@mail.ru
ORCID iD: 0000-0003-0589-7999

MD, Dr. Sci. (Medicine), Associate Professor, Chief Researcher, Professor of the Department of Radiology, Surgery and Oncology

Russian Federation, Saint Petersburg

Oleg A. Bogomolov

Granov Russian Research Center of Radiology and Surgical Technologies

Email: urologbogomolov@gmail.com
ORCID iD: 0000-0002-5860-9076

MD, Cand. Sci. (Medicine), Senior Researcher, Associate Professor of the Department of Radiology, Surgery and Oncology

Russian Federation, Saint Petersburg

Aleksei Yu. Kneev

Granov Russian Research Center of Radiology and Surgical Technologies

Email: alexmedspb@gmail.com
ORCID iD: 0000-0002-5899-8905
SPIN-code: 8015-1529

MD, Cand. Sci. (Medicine), Senior Lecturer of the Department of Radiology, Surgery and Oncology

Russian Federation, Saint Petersburg

Tamara V. Sukhanova

Granov Russian Research Center of Radiology and Surgical Technologies

Email: tamara.sukhanova00@mail.ru
ORCID iD: 0000-0002-2548-0149

Postgraduate Student of the Department of Radiology, Surgery and Oncology

Russian Federation, Saint Petersburg

References

  1. Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023;73(1):17-48. doi: 10.3322/caac.21763
  2. International Agency for Research on Cancer. Russian Federation: new cancer cases and age-standardized incidence rate, 2022. GLOBOCAN 2022. https://gco.iarc.who.int/media/globocan/factsheets/populations/643-russian-federation-fact-sheet.pdf
  3. Shakhzadova AO, Starinsky VV, Lisichnikova IV. Cancer care to the population of Russia in 2022. Siberian journal of oncology. 2023;22(5):5-13. [Шахзадова А.О., Старинский В.В., Лисичникова И.В. Состояние онкологической помощи населению России в 2022 году. Сибирский онкологический журнал. 2023;22(5):5-13]. doi: 10.21294/1814-4861-2023-22-5-5-13
  4. Hong JH, Jeon SS, Lee HM, et al. The Functional Assessment of Cancer Therapy – Prostate (FACT-P) scales in men with prostate cancer: reliability and validity of the Korean version. J Korean Med Sci. 2006;21(2):295-299. doi: 10.3346/jkms.2006.21.2.295
  5. Functional Assessment of Cancer Therapy – Prostate (FACT-P): translation and licensing methodology. 2023. URL: https://www.facit.org/FACITOrg/Questionnaires
  6. Esper P, Mo F, Chodak G, et al. Measuring quality of life in men with prostate cancer using the Functional Assessment of Cancer Therapy – Prostate (FACT-P) instrument. Urology. 1997;50(6):920-928. doi: 10.1016/S0090-4295(97)00459-7
  7. Cella D, Petrylak D, Fishman M, et al. Estimating clinically meaningful changes for the FACT-P in patients with metastatic prostate cancer. Value Health. 2009;12(1):124-129. doi: 10.1111/j.1524-4733.2008.00401.x
  8. Thomsen FB, Brasso K, Klotz LH, et al. Active surveillance for clinically localized prostate cancer – a systematic review. J Surg Oncol. 2014;109(8):830-835. doi: 10.1002/jso.23584
  9. Pham K, Jeldres C, Johnston R, et al. Health-related quality of life for men with low-risk prostate cancer managed with active surveillance compared to a cancer-screening cohort without prostate cancer. J Urol. 2014;191:147. doi: 10.1016/j.juro.2014.02.560
  10. Parker PA, Davis JW, Latini DM, et al. Relationship between illness uncertainty, anxiety, fear of progression and quality of life in men with favorable-risk prostate cancer undergoing active surveillance. BJU Int. 2016;117:469-477. doi: 10.1111/bju.13099
  11. Musunuru HB, Yamamoto T, Klotz L, et al. Active surveillance for intermediate risk prostate cancer: survival outcomes in the Sunnybrook experience. J Urol. 2016;196(6):1651-1658. doi: 10.1016/j.juro.2016.06.102
  12. Klotz L. Active surveillance for low-risk prostate cancer. Curr Urol Rep. 2015;16(4):24. doi: 10.1007/s11934-015-0492-z
  13. Kinsella N, Helleman J, Bruinsma S, et al. Active surveillance for prostate cancer: a systematic review of contemporary worldwide practices. Transl Androl Urol. 2018;7(1):83-97. doi: 10.21037/tau.2017.12.24
  14. Herrera-Caceres JO, Wettstein MS, Goldberg H, et al. Utility of digital rectal examination in a population with prostate cancer treated with active surveillance. Can Urol Assoc J. 2020;14:E453-E457. doi: 10.5489/cuaj.6341
  15. Ercole C, Krebs Prots DT, et al. Patient-reported health related quality-of-life (HRQoL) outcomes of patients on active surveillance: results of a prospective, longitudinal, single-center study. J Urol. 2014;191:e665. doi: 10.1016/j.juro.2014.02.1835
  16. Chen RC, Basak R, Meyer A, et al. Association between choice of radical prostatectomy, external beam radiotherapy, brachytherapy, or active surveillance and patient-reported quality of life among men with localized prostate cancer. JAMA. 2017;317:1141-1150. doi: 10.1001/jama.2017.1652

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2025 Zhuravlev A.A., Shkolnik M.I., Bogomolov O.A., Kneev A.Y., Sukhanova T.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).