Micropulse cyclophoto-coagulation in patients with primary open-angle glaucoma: early results

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Abstract

Aim – to evaluate the efficacy and safety of micropulse transscleral cyclophotocoagulation (MP-TSCPC) procedure in patients with primary open-angle glaucoma (POAG).

Material and methods. The study was conducted in 21 patients with POAG and uncompensated intraocular pressure (IOP) using pharmacotherapy. All patients underwent MP-TSCPC procedure with IRIDEX Cyclo G6 device. The follow-up period lasted for 1 month. During this time, the visual acuity, IOP dynamics, complications, as well as the number of hypotensive drugs used were evaluated. Statistical analysis was performed using STATISTICA 12.0 software.

Results. Among patients with moderate and advanced glaucoma, the IOP reduced by 46.7 (3.3; 64.3) % from baseline values by the end of the follow-up period. The target IOP was achieved in 30.7% of patients. In 75% of patients who achieved target IOP, the number of hypotensive drops used was reduced by 1 component. In all patients with terminal stage glaucoma, pain was relieved, and IOP was reduced by 35.5 (8.4; 41.1) %. No intra- or postoperative complications were reported in any case.

Conclusion. MP-TSCPC can be considered as a relatively safe adjunctive method to achieve target IOP in addition to medical treatment in patients with moderate and advanced glaucoma, as well as appropriate method to control pain in patients with the terminal stage of the disease.

About the authors

V. N. Germanova

Samara State Medical University; Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Author for correspondence.
Email: vngermanova@gmail.com
ORCID iD: 0000-0002-0497-9813

PhD, Associate Professor, Department of Eye Diseases of the Institute of Postgraduate Education, ophthalmologist of Ophthalmic Microsurgery Department No. 3

Russian Federation, Samara; Samara

A. V. Sorokin

Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Email: andreysticky14@gmail.com
ORCID iD: 0009-0009-5659-8500

ophthalmologist of Ophthalmic Microsurgery Department No. 3

Russian Federation, Samara

A. V. Zolotarev

Samara State Medical University; Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Email: a.v.zolotarev@samsmu.ru
ORCID iD: 0000-0002-9107-5221

PhD, Associate Professor, Head of the Department of Eye Diseases of the Institute of Postgraduate Education, Chief Physician

Russian Federation, Samara; Samara

E. V. Karlova

Samara State Medical University; Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Email: karlova@inbox.ru
ORCID iD: 0000-0003-4929-8832

PhD, Associate Professor, Department of Eye Diseases of the Institute of Postgraduate Education, Deputy Chief Physician for Innovation and Technology Development

Russian Federation, Samara; Samara

V. M. Malov

Samara State Medical University

Email: v.m.malov@samsmu.ru
ORCID iD: 0000-0001-7366-7955

PhD, Professor, Department of Eye Diseases of the Institute of Postgraduate Education

Russian Federation, Samara

M. V. Radaykina

Samara State Medical University; Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Email: masha1310@yandex.ru
ORCID iD: 0000-0002-3644-6296

a postgraduate student of the Department of Eye Diseases of the Institute of Postgraduate Education; Head of the Ophthalmic Microsurgery Department No. 3

Russian Federation, Samara; Samara

O. V. Zhukova

Samara State Medical University; Samara Regional Clinical Ophthalmological Hospital named after T.I. Eroshevsky

Email: olga-g@list.ru
ORCID iD: 0000-0003-1246-370X

PhD, Professor, Department of Eye Diseases of the Institute of Postgraduate Education

Russian Federation, Samara; Samara

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Supplementary files

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2. Figure 1. IOP levels during the follow-up period

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3. Figure 2. Hypotensive effect of MP-TSCPC (IOP compared to baseline level, %)

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Copyright (c) 2023 Germanova V.N., Sorokin A.V., Zolotarev A.V., Karlova E.V., Malov V.M., Radaykina M.V., Zhukova O.V.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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