Association of proprotein convertase subtilisine/kexin type 9 (pcsk9) with vessel atherosclerosis of carotid and coronary basins in patients with arterial hypertension

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Abstract

Clinical studies over the past decade have demonstrated the possibility of using the proprotein convertase subtilisin/kexin type 9 (PCSK9) to predict cardiovascular risk in both arterial hypertension and associated conditions. However, the information is contradictory and the evidence base has not been fully assembled. This study is an attempt to predict atherosclerotic vascular disease and the development of cardiovascular complications in patients with arterial hypertension depending on the level of PCSK9.

About the authors

Yulia Yu. Vukolova

Samara State Medical University

Author for correspondence.
Email: yuliavuk@gmail.com

Assistant, Internal Diseases Department

Russian Federation, Samara

Irina V. Gubareva

Samara State Medical University

Email: irigub@rambler.ru

Doctor of Medical Sciences, Head of the Internal Diseases Department

Russian Federation, Samara

Galina I. Kiseleva

Samara State Medical University

Email: kafedravb@yandex.ru

Candidate of Medical Sciences, Director of Teaching, Internal Diseases Department

Russian Federation, Samara

Olga V. Zheltyakova

Road Clinical Hospital at the Station of Samara, JSC “RZD”

Email: makola71@mail.ru

Candidate of Biological Science, Head of CDL

Russian Federation, Samara

Nikolai N. Kryukov

Samara State Medical University

Email: kafedravb@yandex.ru

Honoured Science Worker of Russia, Doctor of Medical Sciences, Professor, Internal Diseases Department

Russian Federation, Samara

References

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Copyright (c) 2020 Vukolova Y.Y., Gubareva I.V., Kiseleva G.I., Zheltyakova O.V., Kryukov N.N.

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