Email this article Evaluation of the antibacterial activity of polyalkenate cement modified with metal-containing nanoparticles
- Authors: Rumyantsev V.A.1, Andreev A.A.1, Frolov G.A.2, Leontieva A.V.1
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Affiliations:
- Tver State Medical University
- Moscow Institute of Steel and Alloys
- Issue: Vol 25, No 2 (2025)
- Pages: 52-55
- Section: DENTISTRY
- URL: https://journals.rcsi.science/2410-3764/article/view/310108
- DOI: https://doi.org/10.35693/AVP678195
- ID: 310108
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Abstract
Aim – assessment of the level of antibacterial effect of polyalkenate (glass ionomer) cement modified with nanoparticles of vanadium oxide (V2O5), aluminum oxide (Al2O3) and magnetite (Fe3O4) in relation to a test culture of Staphylococcus aureus and a mixed microbiota of saliva.
Material and methods. Colloidal aqueous solutions of metals and their oxides with a stabilizer were obtained using the electroerosion method. The polyalkenate cement “Cemion” was saturated with colloidal solutions during mixing. The antimicrobial activity of the modified filling material was evaluated in relation to the mixed microbiota (saliva) and the test culture of S. aureus by the in vitro disco diffusion method.
Results. The exposure time of the seals was 24 hours at 37 °C in the thermostat. As a result, samples 1-5 showed no areas of delayed microbial growth. Sample 6 showed a growth retardation zone: 19 mm on a cup with S. aureus and 15 mm on a cup with mixed microbiota.
Conclusion. Polyalkenate cement modified with a colloidal aqueous solution of magnetite can be effective in preventing recurrent dental caries.
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##article.viewOnOriginalSite##About the authors
Vitalii A. Rumyantsev
Tver State Medical University
Email: rumyancev_v@tvgmu.ru
ORCID iD: 0000-0001-6045-3333
MD, Dr. Sci. (Medicine), Professor, Head of the Department of Periodontology
Russian Federation, TverAleksei A. Andreev
Tver State Medical University
Author for correspondence.
Email: aandreev01@yandex.ru
MD, Dr. Sci. (Medicine), Professor, Head of the Department of Periodontology
Russian Federation, TverGeorgii A. Frolov
Moscow Institute of Steel and Alloys
Email: georgifroloff@yandex.ru
Cand. Sci. (Chemistry), Associate Professor of the Department of Physical Chemistry
Russian Federation, MoscowAureliya V. Leontieva
Tver State Medical University
Email: aurika171900@mail.ru
Assistant at the Department of Microbiology and Virology with a course in Immunology
Russian Federation, TverReferences
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