Talc retinopathy as a result of long-term intravenous drug abuse

Cover Page

Cite item

Full Text

Abstract

Narcotic substances have a pronounced toxic effect on the entire body and can lead to disability. Despite ongoing efforts to combat drug addiction, in today's society, many drugs are available for potential use. Their destructive action leads to numerous adverse ocular and systemic manifestations. The most frequently, the drug-users are people of working age, in whom visual impairment leads to restrictions on labor and social activities.

The article considers a clinical case of talcum retinopathy, which developed as a result of long-term abuse of intravenous drugs; the ophthalmic manifestations and a possible treatment option are described.

About the authors

Angelina D. Matyaeva

S.N. Fedorov Eye Microsurgery Federal State Institution

Email: matyaeva.lina@yandex.ru
ORCID iD: 0000-0001-7543-619X

a resident doctor

Russian Federation, Moscow

Kseniya I. Slastina

S.N. Fedorov Eye Microsurgery Federal State Institution

Author for correspondence.
Email: docslastina@mail.ru
ORCID iD: 0000-0002-8235-2792

a resident doctor

Russian Federation, Moscow

References

  1. Martidis A, Yung CW, Ciulla TA. Talc embolism: a static retinopathy. Am J Ophthalmol. 1997;124(6):841-843. doi: 10.1016/s0002-9394(14)71704-0
  2. AtLee WE Jr. Talc and cornstarch emboli in eyes of drug abusers. JAMA. 1972;219(1):49-51. PMID: 5066587
  3. Kim RW, Juzych MS, Eliott D. Ocular manifestations of injection drug use. Infect Dis Clin North Am. 2002;16(3):607-22. doi: 10.1016/s0891-5520(02)00013-2
  4. Luong PM, Tsui E, Batra NN, Zegans ME. Endogenous endophthalmitis and other ocular manifestations of injection drug use. Curr Opin Ophthalmol. 2019;30(6):506-512. doi: 10.1097/ICU.0000000000000606
  5. Tarantola R, Reichstein D, Morrison D, Agarwal A. Talc retinopathy presenting as multiple retinal arteriolar occlusions. Retin Cases Brief Rep. 2010;4(2):120-2. doi: 10.1097/ICB.0b013e318196b326
  6. Soliman MK, Sarwar S, Hanout M, et al. High-resolution adaptive optics findings in talc retinopathy. Int J Retina Vitreous. 2015;1:10. doi: 10.1186/s40942-015-0009-4
  7. Tran KH, Ilsen PF. Peripheral retinal neovascularization in talc retinopathy. Optometry. 2007;78(8):409-14. doi: 10.1016/j.optm.2007.02.018
  8. Zoumalan CI, Marmor MF. Revisiting talc retinopathy. Arch Ophthalmol. 2007;125(7):988. doi: 10.1001/archopht.125.7.988
  9. Ruys J, de Smet MD, Van de Sompel W. Bilateral talc maculopathy and fibrovascular proliferation in a drug abuser. Retin Cases Brief Rep. 2010;4(2):123-4. doi: 10.1097/ICB.0b013e31819bfa57
  10. El-Jabali F, Cohen S. Images in clinical medicine. Talc retinopathy. N Engl J Med. 2006;354(12):e11. doi: 10.1056/NEJMicm050711
  11. Li J, Tripathi RC, Tripathi BJ. Drug-induced ocular disorders. Drug Saf. 2008;31(2):127-41. doi: 10.2165/00002018-200831020-00003
  12. Bagheri N, Shahlaee A, Sridhar J, Ho AC. En face optical coherence tomography and angiography of talc retinopathy. Acta Ophthalmol. 2016;94(1):103-4. doi: 10.1111/aos.12814

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Figure 1. Photo of the right eye fundus.

Download (227KB)
3. Figure 2. Photo of the left eye fundus.

Download (219KB)
4. Figure 3. Optical coherence tomography of the macular zone.

Download (282KB)
5. Figure 4. The right eye: optical coherence tomography angiography of the macular zone.

Download (787KB)
6. Figure 5. The left eye: optical coherence tomography angiography of the macular zone.

Download (821KB)

Copyright (c) 2023 Matyaeva A.D., Slastina K.I.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).