Results of complex therapy of the central retinal vein occlusion using laser methods of treatment

Cover Page

Cite item

Full Text

Abstract

Aim – to analyze and compare the effectiveness of conservative treatment and complex methods (intravitreal injections of angiogenesis inhibitors and retinal laser coagulation) of the central retinal vein occlusion treatment.

Material and methods. Based on the case histories, there were analyzed the results of central retinal vein occlusion treatment in 40 patients (the average age is 63) who were treated at the Republican Ophthalmological Hospital.

Results. The course of combined therapy including the anti-VEGF injections and retinal laser coagulation showed the best results: a more significant and persistent decrease of retinal edema and a more marked increase of visual acuity, if compared to conservative therapy of the central retinal vein occlusion.

Conclusion. The results obtained allow us to recommend the complex treatment of the central retinal vein occlusion as the best method for fast and persistent elimination of retinal edema, increased visual acuity and prevention of complications.

About the authors

Svetlana V. Aksenova

National Research Ogarev Mordovia State University

Email: aksenova05@rambler.ru
ORCID iD: 0000-0002-0186-5044

PhD, Professor, Hospital Surgery Department with Traumatology and Orthopedics, Eye diseases courses

Russian Federation, Saransk

Evgenia A. Khozina

National Research Ogarev Mordovia State University

Author for correspondence.
Email: eahozina@gmail.com
ORCID iD: 0000-0001-9513-8464

assistant of the Hospital Surgery Department with Traumatology and Orthopedics, Eye diseases courses

Russian Federation, Saransk

Olga A. Vasilyeva

National Research Ogarev Mordovia State University; Dr. Kurenkov Clinic

Email: olga11vasilyeva@gmail.com
ORCID iD: 0000-0002-3329-8283

PhD, Associate professor, Hospital Surgery Department with Traumatology and Orthopedics, Eye diseases courses; an ophthalmologist

Russian Federation, Saransk; Moscow

Tatyana N. Kumaksheva

National Research Ogarev Mordovia State University

Email: tanya.kumaksheva@mail.ru
ORCID iD: 0000-0002-2672-1872

assistant of the Hospital Surgery Department with Traumatology and Orthopedics, Eye diseases courses

Russian Federation, Saransk

References

  1. Shchuko AG, Zlobina AN, Akulenko MV, et al. Laser surgery of vascular pathology of the eye fundus. M., 2014. (In Russ.). [Щуко А.Г., Злобина А.Н., Акуленко М.В., и др. Лазерная хирургия сосудистой патологии глазного дна. М., 2014].
  2. Ip M. Retinal Vein Occlusion Review. The Asia-Pacific Journal of Ophthalmology. 2018;7:40-45. doi: 10.22608/APO.2017442
  3. Sivaprasad S, Amoaku WM, Hykin P, et al. Retinal Vein Occlusion (RVO) Guidelines Royal College of Ophthalmologists. Eye (Lond). 2015;29(12):1633-8.
  4. Altintas AGK. Laser Photocoagulation in Retinal Vein Occlusion. International Journal of Ophthalmic Research. 2016;2(2):143-147. doi: 10.17554/j.issn.2409-5680.2016.02.40
  5. Aliev A–G.D, Maksudova ZN, Zakieva SI, Osmanova A. The role of laser photocoagulation in treatment of retinal vein thrombosis. Russian Journal of Clinical Ophthalmology. 2012;2:59. (In Russ.). [Алиев А.–Г.Д., Максудова З.Н., Закиева С.И., Османова А.Н. Роль лазерной коагуляции в комплексном лечении тромбозов вен сетчатки. Клиническая офтальмология. 2012;2:59].
  6. Nurieva NM. Retinal vein occlusion, features of etiopathogenesis, clinic and diagnostics (literature review). Oftalmologiya. 2014;3(16):115-124. (In Russ.). [Нуриева Н.М. Окклюзия вен сетчатки, особенности этиопатогенеза, клиники и диагностики (обзор литературы).Oftalmologiya. 2014;3(16):115-124].
  7. Scott IU, van Veldhuisen PC, Ip MS, et al. Baseline Factors Associated With 6-Month Visual Acuity and Retinal Thickness Outcomes in Patients With Macular Edema Secondary to Central Retinal Vein Occlusion or Hemiretinal Vein Occlusion. JAMA Ophthalmology. 2017;135(6):639-649. doi: 10.1001/jamaophthalmol.2017.1141
  8. Kabardina EV, Shurygina IP. Сontemporary view of retinal vein thromboses. Kuban Scientific Medical Bulletin. 2019;26(1):187-195. (In Russ.). [Кабардина Е.В., Шурыгина И.П. Cовременные представления о тромбозах вен сетчатки. Кубанский научный медицинский вестник. 2019;26(1):187-195]. doi: 10.25207/1608-6228-2019-26-1-187-195
  9. Kamenskikh TG, Nugaeva NR, Sumarokova ES, Gileva EV. The results of combination therapy of central retinal vein branch thrombosis complicated by cystoid macular edema. Russian Ophthalmological Journal. 2013;6(2):2-23. (In Russ.). [Каменских Т.Г., Нугаева Н.Р., Сумарокова Е.С., Гилева Е.В. Результаты комплексной терапии тромбоза ветвей центральной вены сетчатки, осложненного кистозным макулярным отеком. Российский офтальмологический журнал. 2013;6(2):2-23].
  10. Sosorova DV, Ochirova OC, Selezneva MS, Gatanov AS. Treatment of retinal vein thrombosis. Experience of ophthalmologists of Buryatia. BSU bulletin. Medicine and pharmacy. 2018;2:42-45. (In Russ.). [Сосорова Д.В., Очирова О.Ц., Селезнева М.С., Гатанов А.С. Лечение тромбозов вен сетчатки. Опыт офтальмологов Бурятии. Вестник Бурятского государственного университета. Медицина и фармация. 2018;2:42-45].
  11. Boriskina LN, Potapova VN, Melikhova IA, Polyakova VR. Intravitreal injection of lucentis in combination with retinal laser coagulation in treatment of macular edema induced by the occlusion of the central retinal vein branch. Journal of VolgSMU. 2014;3:53-54. (In Russ.). [Борискина Л.Н., Потапова В.Н., Мелихова И.А., Полякова В.Р. Интравитреальное введение луцентиса в сочетании с лазеркоагуляцией сетчатки в лечении макулярного отека вследствие тромбоза ветви центральной вены сетчатки. Вестник ВолгГМУ. 2014;3:53-54].
  12. Patel A, Nguyen C, Lu . Central Retinal Vein Occlusion: A Review of Current Evidence-based Treatment Options. Middle East African Journal of Ophthalmology. 2016;23(1):44-48 doi: 10.4103/0974-9233.173132

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Figure 1. Macular edema thickness in OCT in the comparison group at the time of the first visit and during treatment.

Download (214KB)

Copyright (c) 2022 Aksenova S.V., Khozina E.A., Vasilyeva O.A., Kumaksheva T.N.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).