TREATMENT OF UTERINE MYOMA IN WOMEN PLANNING PREGNANCY BY FOCUSED ULTRASOUND ABLATION UNDER MRI CONTROL


Cite item

Full Text

Abstract

The purpose of this study is to evaluate the effectiveness of focused ultrasound (FUS) ablation as monotherapy for uterine fibroids in women planning a pregnancy. Of the 195 patients included in the study, long-term pregnancy occurred in 38. At the same time, immediately after FUS ablation, without prescribing additional methods of treatment, 7 patients became pregnant. Given the high frequency of additional surgical treatment methods (conservative myomectomy, hysteroresectoscopy), as well as additional procedures for FUS ablation, this method, despite its high efficacy in treating symptomatic myomas, cannot be recommended by us as the only treatment for uterine fibroids in women planning a pregnancy.

About the authors

Yana R. Malysheva

I.M. Sechenov First Moscow State Medical University

Email: malysheva_yr@mail.ru
MD, postgraduate student of the Department of Obstetrics and Gynecology No. 1 of the Medical Faculty of the I.M. Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation Moscow, 119991, Russian Federation

E. A Sosnova

I.M. Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

References

  1. Verkauf B.S. Myomectomy for fertility enhancement and preservation. Fertil. Steril. 1992; 58: 1-15.
  2. Stewart E.A. Uterine fibroids. Lancet. 2001; 357: 293-8.
  3. Donnez J., Jadoul P. What are the implications of myomas on fertility? A need for a debate? Hum. Reprod. 2002; 17: 1424-30.
  4. Somigliana E., Vercellini P., Daguati R., Pasin R., De Giorgi O., Crosignani P.G. Fibroids and female reproduction: a critical analysis of the evidence. Hum. Reprod. Update 2007; 13: 465-76.
  5. Qidwai G.I., Caughey A.B., Jacoby A.F. Obstetric outcomes in women with sonographically identified uterine leiomyomata. Obstet. Gynecol. 2006;107: 376-82.
  6. Quinn M. Complications of hysterectomy. Obstet. Gynecol. 2001; 98: 518-9.
  7. Davies A., Hart R., Magos A., Hadad E., Morris R. Hysterectomy: surgical route and complications. Eur. J. Obstet. Gynecol. Reprod. Biol. 2002; 104: 148-51.
  8. Stewart E.A., Gedroyc W.M., Tempany C.M., Quade B.J., Inbar Y., Ehrenstein T. et al. Focused ultrasound treatment of uterine fibroid tumors: safety and feasibility of a noninvasive thermoablative technique. Am. J. Obstet. Gynecol. 2003;189: 48-54.
  9. Hindley J., Gedroyc W.M., Regan L., Stewart E., Tempany C., Hynnen K., et al. MRI guidance of focused ultrasound therapy of uterine fibroids: early results. Am. J. Roentgenol. 2004; 183: 1713-9.
  10. Fennessy F.M., Tempany C.M. MRI-guided focused ultrasound surgery of uterine leiomyomas. Acad. Radiol. 2005; 12: 1158-66.
  11. Stewart E.A., Rabinovici J., Tempany C.M., Inbar Y., Regan L., Gastout B. et al. Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids. Fertil. Steril. 2006; 85: 22-9.
  12. Rabinovici J., Inbar Y., Revel A., Zalel Y., Gomori J.M., Itzchak Y. et al. Clinical improvement and shrinkage of uterine fibroids after thermal ablation by magnetic resonance-guided focused ultrasound surgery. Ultra-sound Obstet. Gynecol. 2007; 30: 771-7.
  13. Stewart E.A., Gostout B., Rabinovici J., Kim H.S., Regan L., Tempany C.M. Sustained relief of leiomyoma symptoms by using focused ultrasound surgery. Obstet. Gynecol. 2007; 110: 279-87.
  14. Лядов К.В., Сидорова И.С., Курашвили Ю.Б. Дистанционная неинвазивная аблация тканей фокусированным ультразвуком под контролем магнитно-резонансной томографии в лечении миомы матки. Руководство для врачей. М.; 2008.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2019 Eco-Vector



Согласие на обработку персональных данных

 

Используя сайт https://journals.rcsi.science, я (далее – «Пользователь» или «Субъект персональных данных») даю согласие на обработку персональных данных на этом сайте (текст Согласия) и на обработку персональных данных с помощью сервиса «Яндекс.Метрика» (текст Согласия).