Surgical techniques in the treatment of a patient of reproductive age with giant uterine myoma

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Abstract

The paper presented a clinical case of organ-saving surgical treatment for giant uterine myoma with secondary changes in a 36-year-old woman with unrealized reproductive function. The case testifies to the expediency of an individual approach to each patient with such neoplasms both at examination and during intra- and postoperative management.

About the authors

Anatolii I. Ishchenko

I.M. Sechenov First Moscow State Medical University

Email: 7205502@mail.ru
ORCID iD: 0000-0001-5733-953X

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow

Anton A. Ishchenko

Center of Gynecology and Reproductive Technologies of NMIC “Medical and Rehabilitation Center”

Email: ra2001_2001@mail.ru
ORCID iD: 0000-0002-4476-4972

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Irina D. Khokhlova

I.M. Sechenov First Moscow State Medical University

Author for correspondence.
Email: irhohlova5@gmail.com
ORCID iD: 0000-0001-8547-6750

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Tea A. Dzhibladze

I.M. Sechenov First Moscow State Medical University

Email: djiba@bk.ru
ORCID iD: 0000-0003-1540-5628

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow

Anna D. Komarova

I.M. Sechenov First Moscow State Medical University

Email: dr.ailar7@gmail.com
ORCID iD: 0000-0001-5399-7586

graduate student

Russian Federation, Moscow

Oksana Y. Gorbenko

I.M. Sechenov First Moscow State Medical University

Email: go2601@mail.ru
ORCID iD: 0000-0002-3435-4590

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Irina V. Gadaeva

I.M. Sechenov First Moscow State Medical University

Email: irina090765@gmail.com
ORCID iD: 0000-0003-0144-4984

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Yurii V. Chushkov

I.M. Sechenov First Moscow State Medical University

Email: obstetrics-gynecology@list.ru
ORCID iD: 0000-0001-8125-1829

MD, Cand. Sci. (Medicine)

Russian Federation, Moscow

Ekaterina V. Tevlina

I.M. Sechenov First Moscow State Medical University

Email: tevlina.ekaterina@gmail.com
ORCID iD: 0009-0003-5235-1814
Russian Federation, Moscow

Mikhail B. Ageev

I.M. Sechenov First Moscow State Medical University

Email: mikhaageev@yandex.ru
ORCID iD: 0000-0002-6603-804X

MD, Cand. Sci. (Medicine), Assistant Professor

Russian Federation, Moscow

Adelina G. Ozdemir

I.M. Sechenov First Moscow State Medical University

Email: Adelina.ozdemir00@gmail.com
ORCID iD: 0009-0000-8753-8433

student

Russian Federation, Moscow

References

  1. Yang W, Bryunin DV, Zuev VM, et al. Reconstructive plastic surgery and its impact on the state of the reproductive system in patients with uterine myoma. Russian Bulletin of Obstetrician-Gynecologist. 2022;22(2):85–90. EDN: BSYIRQ doi: 10.17116/rosakush20222202185
  2. Davydov AI, Shakhlamova MN, Novruzova NKh. Submucosal uterine fibroid and endometrial hyperplasia: principles of treatment in the reproductive period. Gynecology, Obstetrics and Perinatology. 2020;19(2):136–142. EDN: CAZZDP doi: 10.20953/1726-1678-2020-2-136-142
  3. Sinchikhin SP, Magakyan SG, Sinchikhina ES, Magakyan GS. Algorithm for the management of patients with uterine fibroids in the preconception period. Gynecology, Obstetrics and Perinatology. 2022;21(6):139–145. EDN: VCUXZV doi: 10.20953/1726-1678-2022-6-139-145
  4. Yang Q, Ciebiera M, Bariani MV, et al. Comprehensive review of uterine fibroids: developmental origin, pathogenesis, and treatment. Endocr Rev. 2022;43(4):678–719. doi: 10.1210/endrev/bnab039
  5. Dorfman MF, Gasparov AS, Dubinskaya ED, et al. Modeling and surgical navigation in treatment of benign ovarian tumors. Obstetrics and Gynecology: News, Opinions, Training. 2023;11(Suppl):18–24. doi: 10.33029/2303-9698-2023-11-suppl-18-24
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  7. Peddada SD, Laughlin SK, Miner K, et al. Growth of uterine leiomyomata among premenopausal black and white women. Proc Natl Acad Sci USA. 2008;105(50):19887–19892. doi: 10.1073/pnas.0808188105
  8. Kalyan S, Sharma S. Giant uterine leiomyoma: a case report with literature review. Int J Reprod Contracept Obstet Gynecol. 2018;7(11):4779–4785. doi: 10.18203/2320-1770.ijrcog20184548
  9. Ikechebelu JI, Okpala BC, Eleje GU, et al. Delayed presentation of giant uterine fibroids in a Nigerian private specialist health facility. SAGE Open Med Case Rep. 2021;9:2050313X211063137. doi: 10.1177/2050313X211063137
  10. Viva W, Juhi D, Kristin A, et al. Massive uterine fibroid: a diagnostic dilemma: a case report and review of the literature. J Med Case Rep. 2021;15(1):344. doi: 10.1186/s13256-021-02959-3
  11. Jonas HS, Masterson BJ. Giant uterine tumors: case report and review of the literature. Obstet Gynecol. 1977;50(1 Suppl):2s–4s.
  12. Ishchenko AA, Gadaeva IV, Chushkov YuV, et al. Reconstructive plastic surgery with fertility preservation in a young woman with giant uterine leiomyoma. Gynecology, Obstetrics and Perinatology. 2023;22(1):122–126. EDN: LTAEAE doi: 10.20953/1726-1678-2023-1-122-126

Supplementary files

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2. Fig. 1. A giant uterine myoma with secondary changes and subserosal node localization.

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3. Fig. 2. Emptying the cavity of a giant myomatous node.

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