The possibility of statusmetric model for managing general cardiovascular risk


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Abstract

Under the control of the total cardiovascular risk means the possibility of targeted reduction of its absolute and relative values through exposure to risk factors that have been proven to affect the progression of atherosclerosis and the development of its clinical complications. The study included 81 people of socially homogeneous group of men working at the same enterprise and being on dispensary dynamic supervision within 10 years who did not have clinical manifestations of atherosclerosis according to the data of primary inspection. The median age was 45.6±2.94 years. The statistical calculations were based on the method of status measurement, which allows to analyze and assess the state of human health by a complex of genetic, immunological, physiological, biochemical, anamnetic and socio-hygienic indicators. The obtained result made it possible to propose an algorithm for assessing the risk of developing clinical manifestations of atherosclerosis for a single sample of individuals, which is simple for use in clinical practice. Thus, the classification capabilities statustitle in the separation of the men surveyed limited sample to alternative on combined endpoints for the subgroup is significantly higher than the possibility of stratification according to the SCORE model for European countries with high risk (sensitivity 73.9 per cent, a specificity of 74.7%).

About the authors

P. V Bovtyushko

S.M.Kirov Medical Military Academy of the Ministry of Defence of the Russian Federation

канд. мед. наук, каф. военно-морской терапии 194044, Russian Federation, Saint Petersburg, ul. Akademika Lebedeva, d. 6

S. L Grishayev

S.M.Kirov Medical Military Academy of the Ministry of Defence of the Russian Federation

Email: grishaev_med@mail.ru
д-р мед. наук, проф., зам. нач. каф. и клиники военно-морской терапии 194044, Russian Federation, Saint Petersburg, ul. Akademika Lebedeva, d. 6

V. S Nikiforov

I.I.Mechnikov State Northwestern Medical University of the Ministry of Health of the Russian Federation

д-р мед. наук, проф. каф. функциональной диагностики 191015, Russian Federation, Saint Petersburg, ul. Kirochnaia, d. 41

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