Spontaneous anterior coronary interventricular artery dissection in a young woman in the late postpartum period: clinical case

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Abstract

BACKGROUND: Cardiovascular complications during pregnancy and postpartum period are rare but often fatal. The causes and mechanisms of the development of such complications are not fully understood. Spontaneous dissection of the coronary artery against the background of the influence of sex hormones is one of the mechanisms for the development of acute coronary syndrome in the postpartum period. The false lumen of the intramural hematoma overlaps the true lumen, causing arterial obstruction, leading to acute myocardial hypoxia. Thus, awareness that the pathophysiology of spontaneous coronary artery dissection differs from that of acute coronary syndrome associated with atherosclerotic plaque rupture is important, and these patients require different treatment approaches. Currently, an unambiguous and precise strategy for this pathology has not been established, which is why difficulties remain in the management of these patients and choosing treatment strategies.

CLINICAL CASE DESCRIPTION: The article describes a complex clinical case of the development of acute myocardial infarction in the postpartum period in a young woman without risk factors against the background of spontaneous dissection of the coronary artery, complicated by cardiogenic shock, which required emergency percutaneous coronary intervention and stenting of the infarct-dependent artery. The postoperative period proceeded with complications, and extracorporeal membrane oxygenation was required. However, an integrated approach and correctly chosen treatment strategies help stabilize the patient’s condition.

CONCLUSION: Currently, no unambiguous and precise strategy of treatment has been established, so difficulties remain in the management of patients and decision making. In our opinion, an individual patient approach should be followed, taking into account the general state of the organism, type and volume of dissection, consequences and complications, and experience and technical capabilities of the clinic.

About the authors

Alena R. Anokhina

Regional Clinical Hospital; Voyno-Yasenetsky Krasnoyarsk State Medical University

Author for correspondence.
Email: alena.anohina.rus@yandex.ru
ORCID iD: 0000-0001-9528-762X
SPIN-code: 9055-9403

cardiologist, department assistant

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk; Krasnoyarsk

Gennady V. Matyushin

Regional Clinical Hospital; Voyno-Yasenetsky Krasnoyarsk State Medical University

Email: matyushin1@yandex.ru
ORCID iD: 0000-0002-0150-6092
SPIN-code: 2398-1156

MD, Dr. Sci. (Med.), Professor, department head

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk; Krasnoyarsk

Sergei A. Ustyugov

Regional Clinical Hospital; Voyno-Yasenetsky Krasnoyarsk State Medical University

Email: ustyugoff-s@yandex.ru
ORCID iD: 0000-0003-3105-1946
SPIN-code: 9045-7075

department head, associate professor

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk; Krasnoyarsk

Evgeny I. Kharkov

Voyno-Yasenetsky Krasnoyarsk State Medical University; Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital

Email: Harkov-50@mail.ru
ORCID iD: 0000-0002-8208-0926
SPIN-code: 1234-3885

MD, Dr. Sci. (Med.), department professor

Russian Federation, Krasnoyarsk; Krasnoyarsk

Elena A. Savchenko

Voyno-Yasenetsky Krasnoyarsk State Medical University; Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital

Email: lenasavchenko@rambler.ru
ORCID iD: 0000-0003-4438-1434
SPIN-code: 2742-2621

MD, Cand. Sci. (Med.), associate professor

Russian Federation, Krasnoyarsk; Krasnoyarsk

Petr N. Vlasov

Regional Clinical Hospital

Email: v.petrn@mail.ru
ORCID iD: 0009-0002-3646-3165

anesthesiologist-resuscitator

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk

Vadim V. Okhrimchuk

Regional Clinical Hospital

Email: vadim_esenin@mail.ru
ORCID iD: 0000-0001-7714-1942

anesthesiologist-resuscitator

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk

Valentin V. Skorobogatov

Regional Clinical Hospital

Email: vaal_z@list.ru
ORCID iD: 0009-0002-6293-4098

cardiologist

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk

Ekaterina V. Popova

Regional Clinical Hospital

Email: veffy@mail.ru
ORCID iD: 0009-0004-8940-7612

cardiologist

Russian Federation, 3A Partizana Zheleznyaka Str., 660022, Krasnoyarsk

Elnur B. Karaev

Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital

Email: elnurmed@mail.ru

cardiologist

Russian Federation, Krasnoyarsk

Natalya Yu. Tsibulskaya

Voyno-Yasenetsky Krasnoyarsk State Medical University; Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital

Email: solna33@yandex.ru
ORCID iD: 0000-0003-0122-0884
SPIN-code: 4238-8156

MD, Cand. Sci. (Med.), associate professor

Russian Federation, Krasnoyarsk; Krasnoyarsk

Evgeny I. Ryabkov

Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital

Email: ryabkov.ei@mail.ru

X-ray surgeon

Russian Federation, Krasnoyarsk

References

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  7. Bockeria LA, Golukhova EZ, Petrosyan KV, et al. Spontaneous coronary dissection: case reports and literature review. Creative Cardiology. 2020;14(1):71–81. (In Russ). doi: 10.24022/1997-3187-2020-14-1-71-81
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Supplementary files

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2. Fig. 1. Electrocardiogram of the patient on admission.

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3. Fig. 2. Results of coronary angiography at admission and after percutaneous coronary intervention. The arrows indicate the sites of dissection of the coronary arteries. Note. The arrows indicate the sites of the coronary arteries dissection.

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