Measles morbidity in the Northwestern Federal District of the Russian Federation
- Authors: Antipova A.Y.1, Zheleznova N.V.1, Tolstykh N.A.1, Kaziakhmedova V.V.1, Gorziy E.S.1, Blokhinova M.A.1, Dumcheva O.S.2, Smirnova N.A.3, Zorina D.M.4, Molchanova Z.R.5, Buts L.V.6, Koltsov N.S.7, Dzhusoeva A.T.7, Dedkova L.S.8, Abramovskaya E.I.9, Smirnova I.K.10, Kalinina E.L.10, Gvozdeva I.S.11, Slepukhina N.L.1, Petukhova M.B.12, Gritsai A.B.13, Kozhemyakina M.A.14, Mironova A.V.15, Dedkov V.G.1
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Affiliations:
- St. Petersburg Pasteur Institute
- Rospotrebnadzor Office for Arkhangelsk region
- Rospotrebnadzor Office for Vologda Region
- Center for Hygiene and Epidemiology in Vologda Region
- Rospotrebnadzor Office for Kaliningrad Region
- Rospotrebnadzor Office for Leningrad Region
- Rospotrebnadzor Office for Murmansk Region
- Rospotrebnadzor Office for Nenets Autonomous Okrug
- Center for Hygiene and Epidemiology in the Arkhangelsk Region and Nenets Autonomous Okrug
- Rospotrebnadzor Office for Novgorod Region
- Department of Rospotrebnadzor for the Republic of Karelia
- Rospotrebnadzor Office for the Komi Republic
- Center for Hugiene and Epidemiology in the Komi Republic
- Higiene and Epidemiology Center in St. Petersburg and Leningrad Region
- Rospotrebnadzor Office for St. Petersburg
- Issue: Vol 15, No 4 (2025)
- Pages: 740-748
- Section: ORIGINAL ARTICLES
- URL: https://journals.rcsi.science/2220-7619/article/view/352123
- DOI: https://doi.org/10.15789/2220-7619-MMI-17867
- ID: 352123
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Abstract
Introduction. The COVID-19 pandemic profoundly affected measles epidemic process. On the territory of the Russian Federation, restrictive measures contributed to the continuation of measles circulation, but the pandemic created the prerequisites for further development of outbreaks. We have to analyze measles morbidity in the Northwestern Federal District in the pre- and post-COVID-19 period.
Material and methods. Blood serum samples (n = 3179) collected from patients with maculopapular rash and fever were studied using ELISA.
Results. In the Russian Federation in the years 2008–2010 measles incidence remained at extremely low level due to the importation of measles virus of different genotypes from global regions. In the territories of the Northwestern Federal District, during the period preceding the COVID-19 pandemic, measles incidence was characterized as sporadic. A major measles outbreak occurred in 2018–2019, with the disease being recorded in 6 of the 11 territories of the Northwestern Federal District. Since the introduction of quarantine measures, the number of verified measles cases has dropped sharply. The last case of measles in the region was reported in May 2020. In 2021, measles was not recorded in the territories of the Northwestern Federal District. The rise in measles incidence began at the late 2022 due to imported measles from Tajikistan. In 2023, measles incidence in the district amounted to 2.5 per 100 000 population. Measles continued to spread in 2024. In 2023 and 2024, the disease occurred mainly in unvaccinated subjects or those with unknown vaccination history; mostly children. The spread of measles in the territories of the Northwestern Federal District in 2022 and early 2023 was facilitated by late diagnosis and isolation of the first measles patients; introduction of measles into population groups not vaccinated against measles; delays in the supply of vaccines for populational immunization, including in outbreak areas. In general, measles circulation has resumed in the territories of the Northwestern Federal District.
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##article.viewOnOriginalSite##About the authors
A. Yu. Antipova
St. Petersburg Pasteur Institute
Author for correspondence.
Email: anti130403@mail.ru
PhD (Biology), Senior Researcher, Laboratory of Experimental Virology
Russian Federation, St. PetersburgN. V. Zheleznova
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
PhD (Biology), Leading Researcher, Laboratory of Viral Hepatitis
Russian Federation, St. PetersburgN. A. Tolstykh
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
PhD (Biology), Senior Researcher, Laboratory of Etiology and Control of Viral Infections
Russian Federation, St. PetersburgV. V. Kaziakhmedova
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
Epidemiologist, Laboratory of Molecular Genetic Diagnostics
Russian Federation, St. PetersburgE. S. Gorziy
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
Junior Researcher, Laboratory of Epidemiology of Infectious and Non-Infectious Diseases
Russian Federation, St. PetersburgM. A. Blokhinova
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
Junior Researcher, Laboratory of Etiology and Control of Viral InfectionsRussian Federation, St. Petersburg
O. S. Dumcheva
Rospotrebnadzor Office for Arkhangelsk region
Email: anti130403@mail.ru
Deputy Head of the Epidemiological Surveillance Department
Russian Federation, ArkhangelskN. A. Smirnova
Rospotrebnadzor Office for Vologda Region
Email: anti130403@mail.ru
Head of the Epidemiological Surveillance Departmen
Russian Federation, VologdaD. M. Zorina
Center for Hygiene and Epidemiology in Vologda Region
Email: anti130403@mail.ru
Head of The Laboratory of Especially Dangerous and Viral Infections
Russian Federation, VologdaZ. R. Molchanova
Rospotrebnadzor Office for Kaliningrad Region
Email: anti130403@mail.ru
Acting Head of the Department of Epidemiological Surveillance and Sanitary Protection
Russian Federation, KaliningradL. V. Buts
Rospotrebnadzor Office for Leningrad Region
Email: anti130403@mail.ru
Head of Epidemiological Surveillance Department
Russian Federation, St. PetersburgN. S. Koltsov
Rospotrebnadzor Office for Murmansk Region
Email: anti130403@mail.ru
Head of the Epidemiological Surveillance Department
Russian Federation, MurmanskA. T. Dzhusoeva
Rospotrebnadzor Office for Murmansk Region
Email: anti130403@mail.ru
Deputy Head of the Epidemiological Surveillance Department
Russian Federation, MurmanskL. S. Dedkova
Rospotrebnadzor Office for Nenets Autonomous Okrug
Email: anti130403@mail.ru
Head Expert Specialist
Russian Federation, ArkhangelskE. I. Abramovskaya
Center for Hygiene and Epidemiology in the Arkhangelsk Region and Nenets Autonomous Okrug
Email: anti130403@mail.ru
Epidemiologist, Nenets Branch
Russian Federation, ArkhangelskI. K. Smirnova
Rospotrebnadzor Office for Novgorod Region
Email: anti130403@mail.ru
Head Specialist-Expert of the Epidemiological Surveillance Department
Russian Federation, Veliky NovgorodE. L. Kalinina
Rospotrebnadzor Office for Novgorod Region
Email: anti130403@mail.ru
Head of the Epidemiological Surveillance Department
Russian Federation, Veliky NovgorodIu. S. Gvozdeva
Department of Rospotrebnadzor for the Republic of Karelia
Email: anti130403@mail.ru
Head of the Epidemiological Surveillance Department
Russian Federation, PetrozavodskN. L. Slepukhina
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
Deputy Head of the Epidemiological Surveillance Department
Russian Federation, St. PetersburgM. B. Petukhova
Rospotrebnadzor Office for the Komi Republic
Email: anti130403@mail.ru
Head of the Epidemiological Surveillance Department
Russian Federation, SyktyvkarA. B. Gritsai
Center for Hugiene and Epidemiology in the Komi Republic
Email: anti130403@mail.ru
Head of the Laboratory of Viral and Natural Focal Infections
Russian Federation, SyktyvkarM. A. Kozhemyakina
Higiene and Epidemiology Center in St. Petersburg and Leningrad Region
Email: anti130403@mail.ru
Head of the Department of Epidemiology, Parasitology and Desinfection
Russian Federation, St. PetersburgA. V. Mironova
Rospotrebnadzor Office for St. Petersburg
Email: anti130403@mail.ru
Head Specialist-Expert
Russian Federation, St. PetersburgV. G. Dedkov
St. Petersburg Pasteur Institute
Email: anti130403@mail.ru
PhD (Medicine), Deputy Director for Scientific Work
Russian Federation, St. PetersburgReferences
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