Preoperative fasting for elective surgery in children

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Abstract

This review investigated preoperative fasting in children who need elective surgical interventions. Fifty publications included in the abstract databases PubMed and elibrary for the period from 2017 to 2023 were reviewed. For the analysis, we used articles on the effect of preoperative fasting on indicators of the cardiovascular system and water and carbohydrate metabolism and assessed the course of the perioperative period depending on the duration of refusal of solid food and liquids before surgery. The article presents historical information that formed the basis for the modern paradigm of refusal of solid food and liquids in the preoperative period, especially the negative consequences of prolonged refusal of food in the preoperative period, indicating the main ones, namely, euglycemic ketosis and ketoacidosis, which are common in children. Hypoglycemia due to food refusal before surgery is rare and is not a serious problem in most patients, except in children in the first year of life. In most cases, it has been demonstrated that the time of preoperative fasting significantly exceeds the recommended intervals and amounts to more than 10 hours, and >75% of patients experience a strong feeling of hunger. Infusion of dextrose solutions has not been found to reduce feelings of hunger and thirst before surgery. An increase in preoperative fasting time is often associated with improper organization of the process (35.1%), an increase in surgical time (34.1%), and surgical plan changes (20.9%). It is noted that the optimal volume of liquid that a child can drink before surgery is <3 ml/kg. Data indicates that preoperative fasting can cause arterial hypotension after induction of anesthesia, at the stage of preparing the surgical field. It has been demonstrated that a residual gastric volume of >1.25 ml/kg is a risk factor for aspiration during the induction of anesthesia. There is currently no convincing evidence of the negative effect of preoperative fasting on treatment outcome; however, clearly, the time to abandon clear liquids before elective surgery in children should be minimal.

About the authors

Yurii S. Aleksandrovich

Saint Petersburg State Pediatric Medical University

Email: Jalex1963@mail.ru
ORCID iD: 0000-0002-2131-4813
SPIN-code: 2225-1630

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Saint Petersburg

Konstantin V. Pshenisnov

Saint Petersburg State Pediatric Medical University

Author for correspondence.
Email: Psh_K@mail.ru
ORCID iD: 0000-0003-1113-5296
SPIN-code: 8423-4294

MD, Dr. Sci. (Medicine), Assistant Professor

Russian Federation, Saint Petersburg

Shoakmal Sh. Shorakhmedov

Saint Petersburg State Pediatric Medical University; Tashkent Pediatric Medical Institute

Email: sshoraxmedovs@gmail.com
ORCID iD: 0000-0002-4695-610X
Russian Federation, Saint Petersburg; Tashkent, Uzbekistan

References

  1. Green SM, Mason KP, Krauss BS. Pulmonary aspiration during procedural sedation: a comprehensive systematic review. Br J Anaesth. 2017;118(3):344–354. doi: 10.1093/bja/aex004
  2. Andersson H, Zarén B, Frykholm P. Low incidence of pulmonary aspiration in children allowed intake of clear fluids until called to the operating suite. Paediatr Anaesth. 2015;25(8):770–777. doi: 10.1111/pan.12667
  3. Beach ML, Cohen DM, Gallagher SM, Cravero JP. Major adverse events and relationship to nil per os status in pediatric sedation/anesthesia outside the operating room: A report of the pediatric sedation research consortium. Anesthesiology. 2016;124(1):80–88. doi: 10.1097/ALN.0000000000000933
  4. Beck CE, Rudolp D, Becke-Jakob K, et al. Real fasting times and incidence of pulmonary aspiration in children: Results of a German prospective multicenter observational study. Paediatr Anaesth. 2019;29(10):1040–1045. doi: 10.1111/pan.13725
  5. Tan Z, Lee SY. Pulmonary aspiration under GA: a 13-year audit in a tertiary pediatric unit. Paediatr Anaesth. 2016;26(5):47–52. doi: 10.1111/pan.12877
  6. Хrykholm P, Schindler E, Sümpelmann R, et al. Preoperative fasting in children: review of existing guidelines and recent developments. Br J Anaesth. 2018;120(3):469–474. doi: 10.1016/j.bja.2017.11.080
  7. Аleksandrovich YuS, Pshenisnov KV. Pre-operative preparation to anesthesia in children. Messenger of anesthesiology and resuscitation. 2020;17(3):79–94. EDN: QZNFOB doi: 10.21292/2078-5658-2020-17-3-79-94
  8. Maltby JR. Fasting from midnight — the history behind the dogma. Best Pract Res Clin Anaesthesiol. 2006;20(3):363–378. doi: 10.1016/j.bpa.2006.02.001
  9. Andersson H, Schmitz A, Frykholm P. Preoperative fasting guidelines in pediatric anesthesia: are we ready for a change? Curr Opin Anaesthesiol. 2018;31(3):342–348. doi: 10.1097/ACO.0000000000000582
  10. Dobson G, Chow L, Flexman A, et al. Guidelines to the practice of anesthesia — Revised edition 2019. Can J Anaesth. 2019;66(1):75–108. doi: 10.1007/s12630-018-1248-2
  11. Assen HE, Hassen AM, Abate A, Liyew B. Preoperative fasting time and its association with hypoglycemia during anesthesia in pediatric patients undergoing elective procedures at tikur anbessa specialized hospital, Addis Ababa, Ethiopia. Biomed Res Int. 2021;14(2021):9166603. doi: 10.1155/2021/9166603
  12. Lee H, Kim JT. Pediatric perioperative fluid management. Korean J Anesthesiol. 2023;76(6):519–530. doi: 10.4097/kja.23128
  13. Mesbah A, Thomas M. Preoperative fasting in children. BJA Education. 2017;17(10):346–350. doi: 10.1093/bjaed/mkx021
  14. Meoli M, Lava SAG, Bronz G, et al. Eu- or hypoglycemic ketosis and ketoacidosis in children: a review. Pediatr Nephrol. 2023;39:1033–1040. doi: 10.1007/s00467-023-06115-5
  15. Kyrou I, Tsigos C. Stress hormones: physiological stress and regulation of metabolism. Curr Opin Pharmacol. 2009;9(6):787–793. doi: 10.1016/j.coph.2009.08.007
  16. Kolb H, Kempf K, Röhling M, et al. Ketone bodies: from enemy to friend and guardian angel. BMC Med. 2021;19(1):313. doi: 10.1186/s12916-021-02185-0
  17. De Cosmi V, Milani GP, Mazzocchi A, et al. The metabolic response to stress and infection in critically ill children: the opportunity of an individualized approach. Nutrients. 2017;9(9):1032. doi: 10.3390/nu9091032
  18. Vetter L, Sümpelmann R, Rudolph D, et al. Short anesthesia without intravenous fluid therapy in children: Results of a prospective non-interventional multicenter observational study. Paediatr Anaesth. 2024;34(5):454–458. doi: 10.1111/pan.14847
  19. Khanna P, Saini K, Sinha R, et al. Correlation between duration of preoperative fasting and emergence delirium in pediatric patients undergoing ophthalmic examination under anesthesia: a prospective observational study. Paediatr Anaesth. 2018;28(6):547–551. doi: 10.1111/pan.13381
  20. Balkaya AN, Yılmaz C, Baytar Ç, et al. Relationship between fasting times and emergence delirium in children undergoing magnetic resonance imaging under sedation. Medicina (Kaunas). 2022;58(12):1861. doi: 10.3390/medicina58121861
  21. Friesen RH, Wurl JL, Friesen RM. Duration of preoperative fast correlates with arterial blood pressure response to halothane in infants. Anesth Analg. 2002;95(6):1572–1576. doi: 10.1097/00000539-200212000-00018
  22. Dennhardt N, Beck C, Huber D, et al. Optimized preoperative fasting times decrease ketone body concentration and stabilize mean arterial blood pressure during induction of anesthesia in children younger than 36 months: a prospective observational cohort study. Paediatr Anaesth. 2016;26(8):838–843. doi: 10.1111/pan.12943
  23. Simpao AF, Wu L, Nelson O, et al. Preoperative fluid fasting times and postinduction low blood pressure in children: a retrospective analysis. Anesthesiology. 2020;133(3):523–533. doi: 10.1097/ALN.0000000000003343
  24. Vutskits L, Davidson A. Fluid fasting in children: solid science? Anesthesiology. 2020;133(3):493–494. doi: 10.1097/ALN.0000000000003406
  25. Himanshu K, Boat A, Singh S. Preoperative fasting amounting to dehydration in pediatrics age group — an observational study. Indian J Appl Res. 2022;12(11):46–48. doi: 10.36106/ijar
  26. Brady M, Kinn S, Ness V, et al. Preoperative fasting for preventing perioperative complications in children. Cochrane Database Syst Rev. 2009;4:CD005285. doi: 10.1002/14651858
  27. Joshi GP, Abdelmalak BB, Weigel WA, et al. 2023 American Society of Anesthesiologists Practice guidelines for preoperative fasting: carbohydrate-containing clear liquids with or without protein, chewing gum, and pediatric fasting duration — A modular update of the 2017 American Society of Anesthesiologists Practice Guidelines for Preoperative Fasting. Anesthesiology. 2023;138(2):132–151. doi: 10.1097/ALN.0000000000004381
  28. Frykholm P, Disma N, Andersson H, et al. Pre-operative fasting in children: A guideline from the European society of anaesthesiology and intensive care. Eur J Anaesthesiol. 2022;39(1):4–25. doi: 10.1097/EJA.0000000000001599
  29. Gamble J, Rosen D. 2023 Canadian Pediatric Anesthesia Society Statement on fasting for elective pediatric anesthesia. Can J Anaesth. 2023;70(8):1295–1299. doi: 10.1007/s12630-023-02509-z
  30. Andersson H. Reduced preoperative fasting in children Acta Universitatis Upsaliensis; 2019. Cited: 2024 Feb 26. Available from: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-394232
  31. Schmitz A, Kellenberger CJ, Liamlahi R, et al. Gastric emptying after overnight fasting and clear fluid intake: a prospective investigation using serial magnetic resonance imaging in healthy children. Br J Anaesth. 2011;107(3):425–429. doi: 10.1093/bja/aer167
  32. Thomas M, Morrison C, Newton R, Schindler E. Consensus statement on clear fluids fasting for elective pediatric general anesthesia. Paediatr Anaesth. 2018;28(5):411–414. doi: 10.1111/pan.13370
  33. Disma N, Frykholm P, Cook-Sather SD, Lerman J. Pro-Con Debate: 1- vs 2-hour fast for clear liquids before anesthesia in children. Anesth Analg. 2021;133(3):581–591. doi: 10.1213/ANE.0000000000005589
  34. Hajian P, Shabani M, Khanlarzadeh E, et al. The impact of preoperative fasting duration on blood glucose and hemodynamics in children. J Diabetes Res. 2020;2020:6725152. doi: 10.1155/2020/6725152
  35. Rawlani SS, Dave NM, Karnik PP. The preoperative fasting conundrum: an audit of practice in a tertiary care children’s hospital. Turk J Anaesthesiol Reanim. 2022;50(3):207–211. doi: 10.5152/TJAR.2022.21132
  36. Yimer AH, Haddis L, Abrar M, Seid AM. Adherence to pre-operative fasting guidelines and associated factors among pediatric surgical patients in selected public referral hospitals, Addis Ababa, Ethiopia: Cross sectional study. Ann Med Surg (Lond). 2022;78:103813. doi: 10.1016/j.amsu.2022.103813
  37. Schmidt AR, Buehler KP, Both C, et al. Liberal fluid fasting: impact on gastric pH and residual volume in healthy children undergoing general anaesthesia for elective surgery. Br J Anaesth. 2018;121(3):647–655. doi: 10.1016/j.bja.2018.02.065
  38. Aroonpruksakul N, Punchuklang W, Kasikan K, et al. The actual duration of preoperative fasting in pediatric patients, and its effects on hunger and thirst: a prospective observational study. Transl Pediatr. 2023;12(2):146–154. doi: 10.21037/tp-22-358
  39. Ricci Z, Colosimo D, Saccarelli L, et al. Preoperative clear fluids fasting times in children: retrospective analysis of actual times and complications after the implementation of 1-h clear fasting. J Anesth Analg Crit Care. 2024;4(1):12. doi: 10.1186/s44158-024-00149-3
  40. de-Aguilar-Nascimento JE, Salomão AB, Waitzberg DL, et al. ACERTO guidelines of perioperative nutritional interventions in elective general surgery. Rev Col Bras Cir. 2017;44(6):633–648. doi: 10.1590/0100-69912017006003
  41. Gawecka A, Mierzewska-Schmidt M. Tolerance of, and metabolic effects of, preoperative oral carbohydrate administration in children — a preliminary report. Anaesthesiol Intensive Ther. 2014;46(2):61–64. doi: 10.5603/AIT.2014.0013
  42. Carvalho CALB, Carvalho AA, Preza ADG, et al. Metabolic and inflammatory benefits of reducing preoperative fasting time in pediatric surgery. Rev Col Bras Cir. 2020;47:e20202353. doi: 10.1590/0100-6991e-20202353
  43. Ying Y, Xu HZ, Han ML. Enhanced recovery after surgery strategy to shorten perioperative fasting in children undergoing non-gastrointestinal surgery: a prospective study. World J Clin Cases. 2022;10(16):5287–5296. doi: 10.12998/wjcc.v10.i16.5287
  44. Spencer AO, Walker AM, Yeung AK, et al. Ultrasound assessment of gastric volume in the fasted pediatric patient undergoing upper gastrointestinal endoscopy: development of a predictive model using endoscopically suctioned volumes. Paediatr Anaesth. 2015;25(3):301–308. doi: 10.1111/pan.12581
  45. Bouvet L, Bellier N, Gagey-Riegel AC, et al. Ultrasound assessment of the prevalence of increased gastric contents and volume in elective pediatric patients: a prospective cohort study. Paediatr Anaesth. 2018;28(10):906–913. doi: 10.1111/pan.13472
  46. Demirel A, Özgünay ŞE, Eminoğlu Ş, et al. Ultrasonographic evaluation of gastric content and volume in pediatric patients undergoing elective surgery: a prospective observational study. Children (Basel). 2023;10(9):1432. doi: 10.3390/children10091432
  47. Miller TE, Myles PS. Perioperative fluid therapy for major surgery. Anesthesiology. 2019;130(5):825–832. doi: 10.1097/ALN.0000000000002603
  48. Sümpelmann R, Becke K, Brenner S, et al. Perioperative intravenous fluid therapy in children: guidelines from the association of the scientific medical societies in Germany. Paediatr Anaesth. 2017;27(1):10–18. doi: 10.1111/pan.13007
  49. Satvaldieva E, Shorakhmedov Sh, Shakarova M, et al. Perioperative fluid therapy as a component of accelerated recovery after surgery (ERAS) in children. International scientific journal. 2023;2(9):22–31. doi: 10.5281/zenodo.8349091
  50. Aleksandrovich YuS, Vorontsova NYu, Grebennikov VА, et al. Recommendations on infusion-transfusion therapy in children undergoing surgery. Messenger of anesthesiology and resuscitation. 2018;15(2):68–84. EDN: XMOGBF doi: 10.21292/2078-5658-2018-15-2-68-84

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