Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause
- 作者: Pestrikova T.Y.1, Yurasova E.A.1, Kovaleva T.D.1, Yurasov I.V.1, Knyazeva T.P.1, Adamyan E.S.1, Mashtagova K.M.1
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隶属关系:
- The Far Eastern State Medical University
- 期: 卷 22, 编号 4 (2020)
- 页面: 49-54
- 栏目: ORIGINAL ARTICLE
- URL: https://journals.rcsi.science/2079-5831/article/view/43872
- DOI: https://doi.org/10.26442/20795696.2020.4.200211
- ID: 43872
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Aim. To evaluate the effectiveness of combination therapy of pathological endometrial processes (benign forms) based on the determination of one of the variants of etiopathogenesis in patients of perimenopausal age and in postmenopause.
Materials and methods. The examination included 34 patients with a diagnosis of endometrial hyperplastic processes in the perimenopausal period and in postmenopause. To verify the diagnosis, in addition to the results of a clinical examination (general and gynecological), the patients underwent laboratory (microscopic and molecular biological studies using real-time polymerase chain reaction method of aspirates from the uterine cavity), diagnostic (ultrasound, hysteroscopy) and morphological examination methods.
Results. Conducting combined antimicrobial and antiviral therapy in patients with endometrial hyperplastic processes, endometrial polyp in combination with chronic endometritis, allowed us to eliminate microbial agents from the endometrium before starting hormonal therapy. A positive result of the combined approach showed the absence of recurrence of endometrial hyperplastic processes within 2 years in 91.17% of patients of the examination group.
Conclusion. In our study, we evaluated the effectiveness of the combined treatment of endometrial hyperplastic processes in patients in the perimenopausal period and in postmenopause, against a background of chronic endometritis, using systemic therapy with antibiotics and antiviral drugs, followed by hormonal therapy. A clinical study allows us to formulate recommendations on the management of patients with endometrial hyperplastic processes, endometrial polyps in the perimenopausal period and in postmenopause.
作者简介
Tatyana Pestrikova
The Far Eastern State Medical University
编辑信件的主要联系方式.
Email: typ50@rambler.ru
D. Sci. (Med.), Prof., The Far Eastern State Medical University
俄罗斯联邦, KhabarovskElena Yurasova
The Far Eastern State Medical University
Email: urasovaea@yandex.ru
D. Sci. (Med.), Prof., The Far Eastern State Medical University
俄罗斯联邦, KhabarovskTamara Kovaleva
The Far Eastern State Medical University
Email: kov-exspress@mail.ru
Cand. Sci. (Med.), The Far Eastern State Medical University
俄罗斯联邦, KhabarovskIgor Yurasov
The Far Eastern State Medical University
Email: ivaiva@yandex.ru
D. Sci. (Med.), Prof., The Far Eastern State Medical University
俄罗斯联邦, KhabarovskT. Knyazeva
The Far Eastern State Medical University
Email: k_t_2002@mail.ru
Cand. Sci. (Med.), The Far Eastern State Medical University
俄罗斯联邦, KhabarovskEvgeniya Adamyan
The Far Eastern State Medical University
Email: yanny_adam@mail.ru
Resident, The Far Eastern State Medical University
俄罗斯联邦, KhabarovskKhava Mashtagova
The Far Eastern State Medical University
Email: khavam@list.ru
Resident, The Far Eastern State Medical University
俄罗斯联邦, Khabarovsk参考
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