Innovations in the diagnosis and treatment of endometriosis: from the current advancements to a future outlook: A review

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Abstract

The search for approaches to diagnosing and treating endometriosis remains a priority in modern gynecology. The extremely high prevalence of this condition and its detrimental effect on somatic and reproductive health and the quality of life of patients determine the need for long-term therapy. The article describes evidence-based, modern guidelines-regulated approaches to the clinical management of patients with endometriosis. Currently, the arsenal of a modern clinician includes several technologies for effective clinical management of such patients (pain management, infertility treatment, monitoring the progression and recurrence of the disease, and quality of life). One such approach is the use of the “gold standard” pharmacotherapy for endometriosis with progestogens, namely dienogest 2 mg, which has been proven not only to relieve symptoms but also to effectively control endometriosis progression and recurrence. The immediate and long-term prospects for the diagnosis and treatment of endometriosis, in particular, drugs with an anti-angiogenic mechanism of action that can potentially change the prognosis of patients with this disease, are also considered.

About the authors

Mekan R. Orazov

Peoples' Friendship University of Russia named after Patrice Lumumba

Author for correspondence.
Email: omekan@mail.ru
ORCID iD: 0000-0002-5342-8129

D. Sci. (Med.)

Russian Federation, Moscow

Viktor E. Radzinsky

Peoples' Friendship University of Russia named after Patrice Lumumba

Email: omekan@mail.ru
ORCID iD: 0000-0003-4956-0466

D. Sci. (Med.), Prof., Acad. RAS

Rwanda, Moscow

Evgeny D. Dolgov

Peoples' Friendship University of Russia named after Patrice Lumumba

Email: omekan@mail.ru
ORCID iD: 0000-0001-6709-5209

Clinical Resident

Russian Federation, Moscow

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