The features of lymph-node reaction to tissue damage in the lymph-drainage area in elderly rats
- Авторлар: Maiborodin I.V.1, Agzaev M.K.1, Ragimova T.M.1, Maiborodina V.I.2
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Мекемелер:
- Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
- Novosibirsk State Medical University
- Шығарылым: Том 7, № 1 (2017)
- Беттер: 35-40
- Бөлім: Article
- URL: https://journals.rcsi.science/2079-0570/article/view/205506
- DOI: https://doi.org/10.1134/S2079057017010106
- ID: 205506
Дәйексөз келтіру
Аннотация
Light microscopy has been used to study the reaction of submandibular lymph nodes (LNs) to surgical damage to the tissues of the maxillofacial region in elderly rats. Connective tissue was more abundant in the LNs of elderly rats than in those of mature animals, regardless of the time of observation (even before surgery). Moreover, the duration of the changes of the volume of the cortical plateau was increased in the old rats, whereas the duration of the changes in paracortex and lymphoid nodules devoid of germinal centers was reduced. The distinctive cytoarchitectonic features included a significant reduction of the number of lymphocytes, mitotic figures, and immuno- and plasmablasts concomitant with the elevation of the number of macrophages, cellular elements that showed signs of destruction, reticulocytes, and red blood cells.
Негізгі сөздер
Авторлар туралы
I. Maiborodin
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
Хат алмасуға жауапты Автор.
Email: imai@mail.ru
Ресей, Novosibirsk, 630090
M. Agzaev
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
Email: imai@mail.ru
Ресей, Novosibirsk, 630090
T. Ragimova
Institute of Chemical Biology and Fundamental Medicine, Siberian Branch
Email: imai@mail.ru
Ресей, Novosibirsk, 630090
V. Maiborodina
Novosibirsk State Medical University
Email: imai@mail.ru
Ресей, Novosibirsk, 630091
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