Age-Related Changes in Sympathetic Innervation of the Stomach in Rats
- Authors: Emanuilov A.I.1, Konovalov V.V.1, Masliukov P.M.1, Polyakov E.L.2, Nozdrachev A.D.3
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Affiliations:
- Yaroslavl State Medical University
- Pavlov Institute of Physiology of the Russian Academy of Sciences
- St. Petersburg State University
- Issue: Vol 9, No 2 (2019)
- Pages: 248-253
- Section: Article
- URL: https://journals.rcsi.science/2079-0570/article/view/206504
- DOI: https://doi.org/10.1134/S2079057019020097
- ID: 206504
Cite item
Abstract
Sympathetic innervation of the stomach is carried out by the prevertebral ganglia of the solar plexus. The localization and neurochemical composition of neurons innervating the stomach in the postnatal ontogenesis of rats have been studied by the method of retrograde axon transport of Fast Blue. In all animals, the celiac ganglia had more labeled neurons than the superior mesenteric ganglion. The number of labeled neurons increased in the first ten days of life and then did not change until senescence. All labeled neurons innervating the stomach contain tyrosine hydroxylase, the catecholamine synthesis enzyme. The proportion of labeled neuropeptide Y-immunopositive neurons did not change during ontogeny; the percentage of labeled calbindin-immunoreactive neurons decreased in the first month of life.
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About the authors
A. I. Emanuilov
Yaroslavl State Medical University
Author for correspondence.
Email: mpm@yma.ac.ru
Russian Federation, Yaroslavl, 150000
V. V. Konovalov
Yaroslavl State Medical University
Email: mpm@yma.ac.ru
Russian Federation, Yaroslavl, 150000
P. M. Masliukov
Yaroslavl State Medical University
Email: mpm@yma.ac.ru
Russian Federation, Yaroslavl, 150000
E. L. Polyakov
Pavlov Institute of Physiology of the Russian Academy of Sciences
Email: mpm@yma.ac.ru
Russian Federation, St. Petersburg, 199034
A. D. Nozdrachev
St. Petersburg State University
Email: mpm@yma.ac.ru
Russian Federation, St. Petersburg, 199034