Prospects for the Use of Genome-Editing Technology to Correct Neurodegenerative Diseases


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Abstract

The review analyzes the results of modern studies that involve gene therapy methods for the correction of neurodegenerative diseases. Approaches based on gene-editing technologies and their prospective use in medicine are considered. There may be limitations to the use of the genome-editing tools in the treatment of these pathologies due to features of the pathogenesis of neurodegenerative diseases.

About the authors

M. Yu. Stepanichev

Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences

Author for correspondence.
Email: m_step_68@mail.ru
Russian Federation, Moscow, 117485


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