Structure and Cytoarchitectonics of Lymphoid Tissue in Appendiсes of Elderly and Senile People

Abstract

The phenomenon of population aging has been observed in many countries in recent years due to the increase in human life expectancy. Therefore, studies of lymphoid tissue, which supports the immune processes in the human body, are now of particular importance. The lymphoid tissue of appendices from humans of age groups of 54–81 years and 26–35 years was histologically studied, and the results were statistically treated. The lymphoid tissue belonging to senile age groups showed reductions and rearrangements with partial integrity of the modified lymphoid nodules. The majority of nodules were without lighter-stained germinal centers, and the processes of blast transformation were preserved therein. Mitoses were observed in the central zones of nodules with lighter centers. Lymphocytes actively migrate to lymphatic capillaries. The condition of lymphoid tissue in the appendix depends on the individual body parameters. In some cases, the lymphoid tissue is completely reduced, and the organ’s lumen is closed.